男科学每日速览

全部累计 · 截至 2026-10-12 · 共 288 条(文献 252 + 器械试验 36)· 逐日追加
全部 男性不育 性功能障碍 器械 / 试验 指南 / 共识 观点
编辑精选 · TOP 5
  1. 1ED 即心血管哨兵(Nature Reviews Urology 综述)
  2. 2CatSper 结构基础综述
  3. 3Li-ESWT vs 径向波头对头试验更新(2026-08-19)
  4. 4AIE 药理启用的细胞器治疗用于微塑料诱导的弱精症
  5. 5放疗后球膜部尿道狭窄重建:吻合 vs 颊黏膜移植 onlay 的狭窄复发风险
一、文献新进展
2026-10-12 星期一 · 当天 45 条
来源:PubMed(按真实发表日,非收录日)· 每条附 PMID 可核对 · 期刊标注 JCR 分区(Q1–Q4,2024 JCR / 2025-06 发布,SJR 核实)
10-10中华医学遗传杂志Case Report仅摘要
[Study of a patient with azoospermia due to variant of MOV10L1 gene].

报道 MOV10L1 变异致唯支持细胞综合征(SCOS)的无精子症男性,分析其临床与基因型特征。

推荐理由

MOV10L1 为精子发生关键基因,扩展国内 NOA 遗传学病因谱,支持基因检测在 NOA 中的常规化。

10-09Eur J Orthop Surg TraumatolJournal ArticleOA全文JCR Q1
Sexual function after pelvic ring fractures: does injury mechanism matter?

探讨骨盆环骨折后性功能障碍与初始损伤机制的关系,骨折常伴神经血管泌尿生殖损伤。

推荐理由

性功能是创伤后长期生活质量的重要指标,提示骨折分型应纳入性功能预后评估。

10-08J Control ReleaseJournal Article仅摘要JCR Q1
Microenvironment-informed carrier-free maltol-arginine nanoparticles harness CAT2-associated arginine transport for spermatogenic disorders.

针对 DEHP 损伤睾丸的氧化应激微环境,构建无载体麦芽酚-精氨酸纳米粒,借 CAT2 精氨酸转运实现病灶靶向蓄积并激活 Nrf2 抗氧化、保护 Leydig 细胞。

推荐理由

为男性不育的抗氧化靶向递送提供新策略,解决传统递送系统睾丸蓄积不足的问题。

10-08J Hum GenetJournal ArticleOA全文JCR Q2
Genotype-phenotype variability in TRMT10A deficiency.

报道 TRMT10A 双等位基因功能缺失变异,一例 34 岁男性表现为男性不育、高度近视、双侧感音神经性耳聋等,区别于典型小头/生长迟缓表型。

推荐理由

扩展 TRMT10A 缺乏症表型谱,提示男性不育可作为其多系统表现之一,利于罕见病识别。

10-08Endocr ConnectCommentary仅摘要JCR Q2
Post-cycle therapy after androgen abuse: what are we seeking to achieve?

评述男性雄激素滥用后"周期后治疗"(PCT)的恢复 HPG 轴目标、生化与症状恢复差异及作为减害策略的潜在角色。

推荐理由

健身人群雄激素滥用普遍而 PCT 证据薄弱,提示需以减害与内分泌随访为重点。

10-07OMICSJournal Article仅摘要JCR Q3
Composition-Aware Analysis of Public Testis Transcriptomes Identifies Reproducible Tissue-State Signatures in Nonobstructive Azoospermia.

用组成感知方法分析公共人睾丸转录组,在 NOA 中鉴定出可重复的"组织状态"特征——生殖细胞(精母/精子细胞)显著耗竭、间质/巨噬细胞相关信号增强;在两个独立 OA 对照队列中验证(效应量 g≈1.70–3.69,置换 p<0.001)。

推荐理由

为 NOA 提供可量化的分子分型信号,有望辅助无创判别与活检决策,减少经验性取精。

10-07Int J Impot ResReviewOA全文JCR Q2
The impact of microplastics on the human reproductive system: a narrative review.

综述微塑料在人血、胎盘、精液、睾丸、阴茎组织检出及其对生殖/性健康(氧化应激、内分泌干扰、ED)的证据,强调人群因果未确立。

推荐理由

环境微塑料是男性生殖健康新兴关注点,需标准化暴露评估与纵向研究。

10-05J Am Chem SocJournal Article仅摘要JCR Q1
Small-Molecule Modulators of HIPK4 Activity and Proteostasis.

报道高效选择性 HIPK4 小分子抑制剂(氰基喹啉类);HIPK4 在精子形成(顶体板/顶体形成)中必需,是男性非激素避孕靶点。

推荐理由

为非激素男性避孕与精子发生机制研究提供化学探针与先导化合物。

10-05Clin ChemJournal Article仅摘要JCR Q1
Accuracy-Based Proficiency Testing Surveys for Testosterone.

评估少数实验室用可互换标本的睾酮测量准确度,及其在男性性腺功能低下阈值附近的分级错误。

推荐理由

睾酮检测准确性直接影响性腺功能减退诊断,提示需标准化与准确度监控。

2026-09-15 星期二 · 当天 4 条
来源:PubMed(按真实发表日,非收录日)· 每条附 PMID 可核对 · 期刊标注 JCR 分区(Q1–Q4,2024 JCR / 2025-06 发布,SJR 核实)
09-15Int ImmunopharmacolJournal Article仅摘要JCR Q1
Electrical stimulation improves arteriogenic erectile dysfunction by modulating CYLD-mediated macrophage-smooth muscle cell crosstalk.

血管性 ED(AED)源于海绵体动脉充盈不足,其复杂病理机制未明、现有治疗存在局限。研究以 cuff 内皮损伤联合高脂饮食建立 AED 大鼠模型,验证"电刺激(ES)通过改善局部免疫微环境、抑制海绵体平滑肌细胞(SMC)病理表型转化而改善 AED"的假说;结果显示 ES 可调节 CYLD 介导的巨噬细胞–SMC 串扰。

推荐理由

提出电刺激经免疫微环境 / CYLD 轴改善血管性 ED 的机制假说,为低强度物理刺激治疗难治性血管性 ED 提供实验依据与潜在新靶点。

09-15CancerJournal ArticleOA全文JCR Q1
Male survivors of childhood cancer and perceptions of sexual dysfunction risk: A report from the Childhood Cancer Survivor Study.

性功能障碍(SD)是儿童癌症被低估的远期后遗症。本研究基于 Childhood Cancer Survivor Study,系统考察男性幸存者性功能障碍感知风险的影响因素。

推荐理由

将男性性功能障碍纳入肿瘤生存者远期健康管理,提示男科 / 肿瘤随访应将 SD 风险沟通与筛查前移,呼应"全生命周期男性健康"视角。

09-12Med Gas ResReviewOA全文JCR Q2
Gas signaling molecule: a new research focus in the treatment of erectile dysfunction.

气体信号分子(一氧化氮、一氧化碳、硫化氢)因可调节血管功能、减轻氧化应激、保护神经与细胞,近期成为 ED 治疗研究的新焦点。本文综述三者参与 ED 发生发展的机制及作为治疗靶点的潜力,重点阐述其改善血管功能、松弛平滑肌、修复神经功能、减少组织纤维化的作用;并总结纳米载体与前药等气体递送策略的研究现状与转化挑战。

推荐理由

将"气体信号分子"系统梳理为 ED 治疗的新兴方向,提示从单一 NO 向多气体协同与靶向递送演进,对研发新型 ED 药物及给药系统具有方向性启发。

09-11Arch Ital Urol AndrolJournal Article仅摘要JCR Q3
Anxiety and erectile function in men with urological disease: a cross-sectional couple-based study.

以夫妻配对(couple-based)框架开展横断面研究,考察合并泌尿疾病的男性中勃起功能的心理与临床预测因素,重点关注焦虑等心理维度对勃起功能的影响。

推荐理由

把"伴侣共同参与"与焦虑维度纳入 ED 评估,提示男科 ED 门诊应常规筛查心理状态并考虑伴侣干预,对优化临床评估路径有现实意义。

2026-09-14 星期一 · 当天 1 条
来源:PubMed(按真实发表日,非收录日)· 每条附 PMID 可核对 · 期刊标注 JCR 分区(Q1–Q4,2024 JCR / 2025-06 发布,SJR 核实)
09-13Clin GenetJournal Article仅摘要JCR Q3
A Homozygous Variant in DMRTB1 Is Associated With Non-Obstructive Azoospermia in Humans.

在一例非梗阻性无精子症(NOA)患者中发现 DMRTB1 新发变异 c.792-797del(p.265-266del),公共数据库罕见、ACMG 预测为疑似致病;SWISS-MODEL 结构建模显示第 254–266 位残基局部构象扰动。睾丸组织 H&E 示精曲小管内成熟精子完全缺失,与 Dmrt6 敲除小鼠表型一致,提示该基因在人类 NOA 发病中的关键作用。

推荐理由

DMRTB1 是迄今新被牵连的人类 NOA 致病基因,可扩展特发性 NOA 的遗传学检测 Panel,并为遗传咨询与潜在靶向干预提供依据;动物模型与临床表型相互印证,证据链较完整。

2026-09-13 星期日 · 当天 14 条
来源:PubMed(按真实发表日,非收录日)· 每条附 PMID 可核对 · 期刊标注 JCR 分区(Q1–Q4,2024 JCR / 2025-06 发布,SJR 核实)
09-13AndrologyEditorialOA全文JCR Q1
Management of Cryptorchidism in Post-pubertal and Adult Age: An Unmet Need in Andrology.

隐睾(睾丸未降)在青春期后及成人中常被忽视,但持续位于腹腔/腹股沟的睾丸存在恶变与不育风险。文章系统梳理成人隐睾的管理缺口,强调早期识别与适时手术/随访的重要性。

推荐理由

隐睾是男性不育与睾丸肿瘤的可干预危险因素,成人期漏诊管理是男科临床的明显短板,对筛查与转诊路径有现实指导意义。

09-13BJU IntJournal ArticleOA全文JCR Q1
Chemotherapy for prostate and renal cell cancers and testosterone supplementation for hypogonadism after prostatectomy.

聚焦前列腺癌/肾细胞癌化疗后及前列腺切除术后性腺功能低下(hypogonadism)的睾酮补充治疗。讨论在肿瘤治疗后如何平衡雄激素补充的获益与安全性。

推荐理由

术后/癌后性腺功能低下影响生活质量与性健康,睾酮补充的时机与禁忌是泌尿-男科交叉的热点,对临床决策有直接参考价值。

09-13Reprod ToxicolReview仅摘要JCR Q2
Influence of radiofrequency electromagnetic radiation on spermatogenesis and sperm function in rodent models: A systematic review.

系统回顾射频电磁场(RF-EMR,如手机/无线设备)对啮齿类动物精子发生与精子功能的影响。数字设备广泛使用使环境暴露与男性生殖健康的关联备受关注。

推荐理由

氧化应激与环境因素是不育的重要可控风险,该综述为男性生殖毒理学与生活方式建议提供了证据基础。

09-13AndrologyJournal ArticleOA全文JCR Q1
Author Reply: Erectile Dysfunction, Anxiety, Perceived Stress, and Insomnia Are More Common Among Acquired Premature Ejaculation Patients in Contrast to Other Premature Ejaculation Syndromes.

作者回复重申获得性早泄(acquired PE)患者较其他早泄综合征更易合并 ED、焦虑、感知压力与失眠。强调心理状态与性功能的双向关联。

推荐理由

性功能障碍常共病精神心理因素,提示早泄诊疗需整合心理评估与综合治疗,而非单纯药物。

09-13Reprod ToxicolJournal Article仅摘要JCR Q2
Microplastics as trojan horses: A new perspective on bisphenol toxicity in male infertility and assisted reproduction.

提出微塑料作为「特洛伊木马」载体增强双酚类(bisphenol)内分泌干扰物对男性不育与辅助生殖(ART)结局的毒性。双酚普遍存在于环境,与男性生殖功能障碍及 ART 不良结局相关。

推荐理由

环境内分泌干扰物通过新型载体放大生殖毒性,为男性不育的环境病因与 ART 安全保障提供新视角。

09-12AndrologyReview仅摘要JCR Q1
The Impact of Common Medications on Male Fertility: An Updated Systematic Review.

更新系统综述常用药物(相较细胞毒药物更常被处方)对备孕男性生育力的潜在影响。药物可通过影响促性腺激素轴、精子发生、附睾成熟等途径改变男性生育力。

推荐理由

备孕男性常服用降压药、抗抑郁药等,其对生育的影响常被忽视,该综述为用药咨询与生育保护提供循证依据。

09-11Asian J AndrolResearch Article仅摘要JCR Q2
Transmembrane protein 196-mediated regulation of CatSper channel through STAT3 phosphorylation influences sperm motility in mammals.

发现跨膜蛋白 TMEM196 通过 STAT3 磷酸化调控精子特异性钙离子通道 CatSper,影响哺乳动物精子活力。TMEM196 缺失雄鼠生育力下降、精子 Ca²⁺浓度与活力降低。

推荐理由

CatSper 是男性不育(弱精)的关键离子通道,揭示 TMEM196–STAT3–CatSper 轴为弱精症机制研究与靶向干预提供新线索。

09-08Mol Cell ProteomicsResearch Article仅摘要JCR Q1
Comparative Lactylomic Profiling Unveils Dynamic Reprogramming of Post-Translational Lactylation Landscapes During Human Sperm Capacitation.

首次系统绘制人精子获能(capacitation)过程中的赖氨酸乳酸化(lactylation)修饰动态图谱。发现获能依赖的乳酸化显著上调/下调,连接代谢重编程与精子超活化运动。

推荐理由

乳酸化是新兴的翻译后修饰,该研究揭示其在男性生殖(精子功能)中的未知作用,为弱精/受精机制提供代谢层面的新解释。

09-08Sex MedResearch ArticleOA全文JCR Q2
An open-label, single-dose, randomized, parallel-group study of the safety and relative bioavailability of topical sildenafil cream vs oral sildenafil in healthy male adults.

比较外用西地那非乳膏与口服西地那非在健康成年男性中的安全性与相对生物利用度。外用制剂旨在降低全身暴露、减少 PDE5 抑制剂(尤其对合并严重心血管疾病男性)的系统性副作用。

推荐理由

ED 一线为口服 PDE5 抑制剂但系统性副作用限制使用,局部西地那非乳膏若证实等效且更安全,将为 ED(尤其心血管共病人群)提供新给药选择。

09-07J Assist Reprod GenetResearch ArticleOA全文JCR Q2
A catalytically competent sperm PLCzeta variant causes fertilization failure through protein insufficiency.

精子 PLCζ p.Arg385Gln(R385Q)变异见于复发性受精失败的不育患者,且精子 PLCζ 水平显著降低。研究明确该变异通过蛋白量不足(而非催化失活)导致受精失败。

推荐理由

PLCζ 缺陷是不明原因受精失败的重要遗传病因,明确机制有助于 ICSI 患者的遗传咨询与精准诊断。

09-07Anal MethodsMethods仅摘要JCR Q3
Quantification of tadalafil in HLMs using an ultrafast UPLC-MS/MS method to assess metabolic stability, including in silico analysis of metabolic lability, DEREK alerts, and ADME characteristics.

建立超快 UPLC-MS/MS 方法在人肝微粒体(HLM)中定量他达拉非(tadalafil,ED/良性前列腺增生/肺动脉高压一线用药)并评估其代谢稳定性。方法 1 分钟内完成检测、线性宽、精密度高。

推荐理由

他达拉非是 ED 一线 PDE5 抑制剂,其代谢稳定性与用药安全评价依赖可靠定量方法,该工作服务于 ED 药物的药代与安全性研究。

09-07J Cell BiolResearch ArticleOA全文JCR Q1
Meiotic CENP-C supports centromere assembly and kinetochore recruitment in spermatogenesis.

以果蝇雄性减数分裂为模型,阐明 CENP-C 在前期 I 维持着丝粒、并在减数分裂动粒招募与功能中的关键作用,及其在减数分裂 II 后的 CID(CENP-A)组装。

推荐理由

着丝粒/动粒机制异常可导致精子发生障碍与男性不育,该基础发现支撑生精减数分裂异常的病理机制理解。

09-07Fr J UrolResearch Article仅摘要JCR Q4
For couples in assisted reproduction programmes, concurrent male and female infection with human papillomavirus might be associated with a longer time to clinical pregnancy and a lower live birth rate.

前期研究发现不育男性 HPV 状态与精子异常(少/弱/畸精)相关;本文进一步提示辅助生殖夫妇双方 HPV 感染可能延长临床妊娠时间、降低活产率。

推荐理由

HPV 与男性精液参数及 ART 结局的关联逐渐被认识,提示不育男性 HPV 筛查与夫妇同查在生殖门诊的潜在价值。

2026-09-12 星期六 · 当天 6 条
来源:PubMed(按真实发表日,非收录日)· 每条附 PMID 可核对 · 期刊标注 JCR 分区(Q1–Q4,2024 JCR / 2025-06 发布,SJR 核实)
09-12Health Sci RepJournal ArticleOA全文JCR Q2
Assessment of Associations Between Demographic Characteristics, Lifestyle Factors, and Sperm Quality Among Men Presenting With Infertility Complaints.

聚焦男性不育方向(Health Sci Rep, 2026-09-12)。 Infertility is a significant global health concern affecting couples worldwide, with male factors contributing to approximately half of all cases. Given regional variations in reproductive determinant…

推荐理由

男性不育相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-12Anim Reprod SciJournal Article仅摘要JCR Q1
Decoding canine male reproductive dysfunction: a multi-level assessment of sperm quality in dogs from the 'Land of Fires' (Campania, Italy).

聚焦男科相关方向(Anim Reprod Sci, 2026-09-12)。 Male canine infertility is increasingly recognized in clinical practice, yet diagnostic workups are often limited to conventional semen parameters. Building on our previous characterization of testicu…

推荐理由

男科相关相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-12Int J Gynaecol ObstetJournal Article仅摘要JCR Q1
The new WHO infertility guideline: A universal right to equitable, evidence-based fertility care.

聚焦男性不育方向(Int J Gynaecol Obstet, 2026-09-12)。 The WHO 'Guideline for the prevention, diagnosis and treatment of infertility' heralds a significant global shift towards recognizing infertility as a medical condition requiring prevention, diagnosis…

推荐理由

男性不育相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-12Appl Biochem BiotechnolJournal ArticleOA全文JCR Q2
Amphora Coffeaeformis Extract as a Novel Therapeutic Agent against Gamma Radiation-Induced Infertility in Male Rats.

聚焦男性不育方向(Appl Biochem Biotechnol, 2026-09-12)。 Gamma irradiation is a well-established environmental and therapeutic hazard known to impair male reproductive function through oxidative stress, hormonal disruption, and structural damage to testicul…

推荐理由

男性不育相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-12Radiother OncolJournal Article仅摘要JCR Q1
Testosterone monitoring and supplementation in patients with intermediate- or high-risk prostate cancer treated with 6-36&#x202f;months of androgen deprivation therapy and radiotherapy: a systematic literature review.

聚焦性腺功能低下/睾酮方向(Radiother Oncol, 2026-09-12)。 Androgen deprivation therapy (ADT) combined with curative-intent radiotherapy is a cornerstone for intermediate- and high-risk localised prostate cancer, yet the clinical relevance of testosterone (T)…

推荐理由

性腺功能低下/睾酮相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-12AndrologyJournal Article仅摘要JCR Q1
Meiotic Origins of Non-Mosaic Klinefelter Syndrome (47, XXY): Mechanisms, Dimorphism, and Emerging Genetic Susceptibility.

聚焦Klinefelter综合征方向(Andrology, 2026-09-12)。 Non-mosaic Klinefelter syndrome (47,XXY) arises from sex-specific meiotic mechanisms leading to nondisjunction during gametogenesis. In maternal cases, errors occur predominantly during meiosis I, fre…

推荐理由

Klinefelter综合征相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

2026-09-11 星期五 · 当天 16 条
来源:PubMed(按真实发表日,非收录日)· 每条附 PMID 可核对 · 期刊标注 JCR 分区(Q1–Q4,2024 JCR / 2025-06 发布,SJR 核实)
09-11Cell Biochem FunctJournal Article仅摘要JCR Q2
Melatonin Regulates Growth-Arrest and DNA-Damage Genes GADD153, GADD45g and GADD34 in Experimental Varicocele.

聚焦精索静脉曲张方向(Cell Biochem Funct, 2026-09-11)。 This study aimed to reveal the relationship between experimental varicocele and melatonin levels. Forty adult Wistar albino rats were used in this study. Control (C), Melatonin (M), Varicocele (V), Va…

推荐理由

精索静脉曲张相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-11Reprod SciJournal ArticleOA全文JCR Q1
Live Birth Following Microdissection Testicular Sperm Extraction and Intracytoplasmic Sperm Injection: A Case Study of a Patient with Non-Obstructive Azoospermia and a Y-chromosome Microdeletion (Ym9; P3, Including AZFb, c Region).

聚焦无精子症方向(Reprod Sci, 2026-09-11)。 The azoospermia factor (AZF) region on the long arm of the Y chromosome is instrumental in spermatogenesis. In particular, complete deletion of the AZFa, AZFb, and AZFb&#x2009;+&#x2009;c regions is no…

推荐理由

无精子症相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-11UrologyJournal Article仅摘要JCR Q2
Microsurgical Denervation of the Penis for Lifelong Premature Ejaculation: A Prospective Multicenter Study Evaluating Technique Modification and Early Clinical Outcomes.

聚焦早泄方向(Urology, 2026-09-11)。 To prospectively assess the clinical outcomes and safety of microsurgical denervation of the penis (MSDP) for treatment of lifelong premature ejaculation (LPE); and to examine the impact of transition…

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早泄相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-11Reprod SciJournal ArticleOA全文JCR Q1
Identification of a Novel Splice-Site variant in TACR3 (c.888&#x2009;+&#x2009;1G&#x2009;&gt;&#x2009;A) Associated with Asthenozoospermia and Hypogonadotropic Hypogonadism in an Iranian Family.

聚焦性腺功能低下/睾酮方向(Reprod Sci, 2026-09-11)。 TACR3 encodes the receptor for neurokinin B, a key regulator of the hypothalamic-pituitary-gonadal axis. Disruption of this pathway can impair gonadotropin release and male reproductive function. Give…

推荐理由

性腺功能低下/睾酮相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-11Adv Mind Body MedJournal Article仅摘要JCR Q3
Healing Through Intimacy: A Systematic Review of Sexual Health as a Mind-Body Medicine Approach.

聚焦性健康/性心理方向(Adv Mind Body Med, 2026-09-11)。 Sexual health is shaped by vascular, pelvic, interoceptive, and interpersonal factors. Mind-body interventions have emerged as potential treatments for sexual dysfunction.

推荐理由

性健康/性心理相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-11Clin Transl MedJournal ArticleOA全文JCR Q1
Testicular toll with viral intrusion: Molecular insights into the impact of chronic HIV infection on male fertility.

聚焦男科相关方向(Clin Transl Med, 2026-09-11)。 Human immunodeficiency virus (HIV) infection remains a major global health concern, compromising immune function and increasing susceptibility to opportunistic infections. Over the past two decades, f…

推荐理由

男科相关相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-11Public HealthJournal Article仅摘要JCR Q1
Associations of age, health literacy, BMI, tobacco use, and COVID-19 infection history with sexual dysfunction among COVID-19 survivors: A multicenter study.

聚焦性健康/性心理方向(Public Health, 2026-09-11)。 Sexual dysfunction is a prevalent and often overlooked issue among COVID-19 survivors. This study aimed to investigate the factors associated with sexual dysfunction in this population.

推荐理由

性健康/性心理相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-11Curr Opin UrolJournal ArticleOA全文JCR Q2
De-escalation surgery for localized prostate cancer: rationale and future direction of precision prostatectomy.

聚焦前列腺方向(Curr Opin Urol, 2026-09-11)。 The evolution of radical prostatectomy has resulted in excellent oncologic outcomes; however, postoperative erectile dysfunction remains a clinical constraint. While oncologic control in focal therapy…

推荐理由

前列腺相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-11J Histochem CytochemJournal ArticleOA全文JCR Q1
Extracellular Matrix Alterations and the Antifibrotic Role of Mycophenolate Mofetil in a Model of Peyronie's Disease.

聚焦Peyronie病/阴茎弯曲方向(J Histochem Cytochem, 2026-09-11)。 Peyronie's disease (PD) is a fibrotic disorder of the tunica albuginea marked by extracellular matrix (ECM) remodeling, leading to penile curvature and erectile dysfunction. This study aimed to evalua…

推荐理由

Peyronie病/阴茎弯曲相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-11Reprod SciJournal ArticleOA全文JCR Q1
Dysregulation of Sphingolipid Metabolism in Non-Obstructive Azoospermia: Insights from Bioinformatics and a Busulfan-Induced Mouse Model.

聚焦无精子症方向(Reprod Sci, 2026-09-11)。 Sphingolipid metabolism plays an important role in regulating essential cellular processes, including apoptosis, proliferation, differentiation, and cellular signaling, which are critical for normal s…

推荐理由

无精子症相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-11Br J OphthalmolJournal Article仅摘要JCR Q1
Erectile dysfunction and the risk of glaucoma in men: a prospective nested case-control study using large-scale UK primary care data.

聚焦勃起功能障碍(ED)方向(Br J Ophthalmol, 2026-09-11)。 Primary open-angle glaucoma (POAG) is a leading cause of irreversible sight loss worldwide. A vascular mechanism has been proposed in POAG pathogenesis but supporting evidence remains limited. This st…

推荐理由

勃起功能障碍(ED)相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-11Urol PractJournal Article仅摘要JCR Q2
Synchronous versus Staged Implantation of Inflatable Penile Prosthesis and Artificial Urinary Sphincter: A Nationwide Analysis of Infection and Revision Outcomes.

聚焦阴茎/假体方向(Urol Pract, 2026-09-11)。 The timing of implantation of inflatable penile prostheses (IPP) and artificial urinary sphincters (AUS) in patients requiring both devices remains controversial, with limited data comparing outcomes…

推荐理由

阴茎/假体相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-11Asian J AndrolJournal Article仅摘要JCR Q2
Efficacy and safety of simenafil in erectile dysfunction: a phase II, randomized, double-blind, placebo-controlled, crossover study.

聚焦勃起功能障碍(ED)方向(Asian J Androl, 2026-09-11)。 Simenafil, a newly developed oral phosphodiesterase type 5 (PDE5) inhibitor, substantially improves erectile function; however, its efficacy has not been evaluated via RigiScan monitoring. This study…

推荐理由

勃起功能障碍(ED)相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-11AndrologyJournal Article仅摘要JCR Q1
Ballelic Variants of TTC-Related Genes Cause Asthenoteratozoospermia With Favorable Clinical Outcomes After ICSI.

聚焦畸精症方向(Andrology, 2026-09-11)。 Male infertility is a complex, multifactorial disorder that affects &#x223c;7% of men worldwide. Variants in DNAH and CFAP genes are well-established causes of asthenoteratozoospermia, but the contrib…

推荐理由

畸精症相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

2026-09-10 星期四 · 当天 11 条
来源:PubMed(按真实发表日,非收录日)· 每条附 PMID 可核对 · 期刊标注 JCR 分区(Q1–Q4,2024 JCR / 2025-06 发布,SJR 核实)
09-10Mol Reprod DevJournal Article仅摘要JCR Q2
JMJD3 Deficiency Alters H3K27me3 Landscapes and Adhesion-Related Transcriptional Programs in Aged Spermatogonia.

聚焦男科相关方向(Mol Reprod Dev, 2026-09-10)。 Spermatogonial stem cells (SSCs) sustain spermatogenesis throughout life by generating differentiating spermatogonia, spermatocytes, and spermatozoa. During this process, male germ cells are interconn…

推荐理由

男科相关相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-10Int J Biol MacromolJournal Article仅摘要JCR Q1
Hydrolyzed eggshell membrane-calcium chelation complex for enhanced antimicrobial activity, antioxidant defense, and male reproductive homeostasis function.

聚焦男科相关方向(Int J Biol Macromol, 2026-09-10)。 Male infertility is strongly associated with oxidative stress-induced damage to sperm structure and function, necessitating bioactive systems capable of regulating redox balance and calcium homeostasi…

推荐理由

男科相关相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-10Eur J Obstet Gynecol Reprod BiolJournal Article仅摘要JCR Q2
The impact of the COVID-19 pandemic on the global burden of infertility: An interrupted time-series analysis of the global burden of disease study 2023.

聚焦男性不育方向(Eur J Obstet Gynecol Reprod Biol, 2026-09-10)。 The COVID-19 pandemic caused widespread disruptions to reproductive healthcare services and raised concerns regarding potential adverse effects on fertility. However, no study has quantified whether t…

推荐理由

男性不育相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-10Digit HealthJournal ArticleOA全文JCR Q2
Digital health nursing in male infertility: Leadership, workforce, and policy pathways for equitable care.

聚焦男性不育方向(Digit Health, 2026-09-10)。 Digital health technologies are reshaping reproductive care, yet their application to male infertility-an area marked by stigma, delayed help-seeking, and structural invisibility-remains underdevelope…

推荐理由

男性不育相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-10Reprod Med BiolJournal ArticleOA全文JCR Q1
Reassessing Semen Analysis: Clinical Insights Beyond Sperm Count and Motility.

聚焦精液/精液组学方向(Reprod Med Biol, 2026-09-10)。 Semen analysis (SA), recognized by the World Health Organization (WHO) as the cornerstone of male infertility evaluation, remains indispensable in reproductive medicine. However, advances in assisted…

推荐理由

精液/精液组学相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-10Perspect Sex Reprod HealthJournal Article仅摘要JCR Q2
Self-Care for Sexual and Reproductive Health: Results From the French 2023 National Survey on Sexuality and Sexual Health.

聚焦性健康/性心理方向(Perspect Sex Reprod Health, 2026-09-10)。 Digital platforms have accelerated sexual and reproductive health (SRH) self-care practices, but evidence is limited regarding the demand and usage of these resources and their potential to reduce SRH…

推荐理由

性健康/性心理相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-10AndrologyJournal Article仅摘要JCR Q1
The Need for a Global Registry for Charting the Natural History of Klinefelter Syndrome.

聚焦Klinefelter综合征方向(Andrology, 2026-09-10)。 Although Klinefelter Syndrome (KS) represents the most common sex chromosome aneuploidy, several gaps in knowledge persist regarding optimal management of individuals with this condition. Individuals…

推荐理由

Klinefelter综合征相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-10AndrologyJournal Article仅摘要JCR Q1
Epididymal Versus Testicular Sperm for ICSI in Obstructive Azoospermia: Embryological, Clinical, and Neonatal Outcomes in a Retrospective Cohort.

聚焦无精子症方向(Andrology, 2026-09-10)。 Whether sperm source influences intracytoplasmic sperm injection (ICSI) outcomes in men with obstructive azoospermia (OA) remains uncertain.

推荐理由

无精子症相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-10Curr Opin UrolJournal Article仅摘要JCR Q2
Surgical techniques that improve urinary continence and sexual outcomes in patients undergoing robotic prostatectomy for prostate cancer: a narrative review.

聚焦性健康/性心理方向(Curr Opin Urol, 2026-09-10)。 Despite several advancements in the surgical technique of robotic prostatectomy, urinary incontinence and sexual dysfunction remain as significant side effects. The purpose of this review is to compar…

推荐理由

性健康/性心理相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

2026-09-09 星期三 · 当天 7 条
来源:PubMed(按真实发表日,非收录日)· 每条附 PMID 可核对 · 期刊标注 JCR 分区(Q1–Q4,2024 JCR / 2025-06 发布,SJR 核实)
09-09Arch ToxicolJournal ArticleOA全文JCR Q1
Lipid&#x2011;disrupting effects of an organochlorine mixture in Sertoli TM4 cells reveal testicular obesogen mechanisms.

聚焦男科相关方向(Arch Toxicol, 2026-09-09)。 Male reproductive health is declining globally, reflected by reduced sperm counts, impaired semen quality, increasing infertility, and a rising incidence of testicular cancer. Endocrine&#x2011;disrupt…

推荐理由

男科相关相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-09Pest Manag SciJournal ArticleOA全文JCR Q1
The testis-specific gene SfGSTe11 regulates eupyrene sperm morphogenesis and is indispensable for male reproduction in a global pest, Spodoptera frugiperda.

聚焦睾丸/生精方向(Pest Manag Sci, 2026-09-09)。 The fall armyworm, Spodoptera frugiperda, is a devastating agricultural pest whose rapid population expansion and increasing crop damage are driven by its exceptional reproductive capacity. While glut…

推荐理由

睾丸/生精相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-09EMBO RepJournal ArticleOA全文JCR Q1
Basal body docking failure triggers centriole clustering and elimination in mammalian spermatogenesis.

聚焦精子发生/生精方向(EMBO Rep, 2026-09-09)。 Cilia are microtubule-based organelles essential for signaling and motility, and their dysfunction causes ciliopathies often associated with infertility. In male germ cells, two types of cilia are pre…

推荐理由

精子发生/生精相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-09Case Rep UrolJournal ArticleOA全文JCR Q2
Intraoperative Ultrasound-Guided Repair of Penile Fracture: A Case Report.

聚焦阴茎/假体方向(Case Rep Urol, 2026-09-09)。 Penile fracture is a rare urological emergency resulting from rupture of the tunica albuginea during blunt trauma to an erect penis, typically during sexual intercourse. While immediate surgical repai…

推荐理由

阴茎/假体相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-09Reprod SciJournal ArticleOA全文JCR Q1
FFAR4 Mediates High-Altitude Hypoxia-Induced Asthenozoospermia through Oxidative Stress and Mitochondrial Dysfunction: An Integrative Bioinformatics and Experimental Study.

聚焦男科相关方向(Reprod Sci, 2026-09-09)。 High-altitude hypoxia is a significant environmental factor contributing to male infertility, particularly asthenozoospermia, yet the underlying molecular mechanisms remain elusive. To address this, w…

推荐理由

男科相关相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-09Arch Ital Urol AndrolJournal Article仅摘要JCR Q3
Association of testicular MRI findings with spermatogenic status and intratesticular sperm in patients with azoospermia or cryptozoospermia.

聚焦无精子症方向(Arch Ital Urol Androl, 2026-09-09)。 The pathophysiology and presence of intratesticular sperm in patients with azoospermia are usually assessed based on clinical findings, hormonal evaluation, and ultrasonography; however, assessment ba…

推荐理由

无精子症相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-09Brain Behav ImmunJournal Article仅摘要JCR Q1
Chronic psychological stress impairs sperm quality via a gut-endotoxin-testis axis.

聚焦睾丸/生精方向(Brain Behav Immun, 2026-09-09)。 Chronic psychological stress is increasingly recognized as a risk factor for male infertility, but the underlying mechanisms remain incompletely understood. This study aimed to investigate whether chr…

推荐理由

睾丸/生精相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

2026-09-08 星期二 · 当天 6 条
来源:PubMed(按真实发表日,非收录日)· 每条附 PMID 可核对 · 期刊标注 JCR 分区(Q1–Q4,2024 JCR / 2025-06 发布,SJR 核实)
09-08Reprod Domest AnimJournal ArticleOA全文JCR Q2
Use of Sildenafil Citrate for the Treatment of Erectile Dysfunction in Stallions: First Case Reports.

聚焦勃起功能障碍(ED)方向(Reprod Domest Anim, 2026-09-08)。 Pharmacological aids can be useful alternatives to enhance penile erection and/or improve ejaculatory function, thereby prolonging the reproductive life of stallions with ejaculatory disorders. This s…

推荐理由

勃起功能障碍(ED)相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-08Ecotoxicol Environ SafJournal Article仅摘要JCR Q1
Machine learning-driven proteomic profiling reveals seminal plasma biomarkers linking trihalomethane exposure to impaired sperm quality.

聚焦精液/精液组学方向(Ecotoxicol Environ Saf, 2026-09-08)。 The decline in sperm quality has emerged as a major public health concern with significant implications for male fertility and population sustainability. However, high-accuracy biomarkers for sperm qu…

推荐理由

精液/精液组学相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-08Ecotoxicol Environ SafJournal Article仅摘要JCR Q1
DEHP-induced male reproductive toxicity: Evidence from population studies, animal experiments, and multi-omics profiling.

聚焦男科相关方向(Ecotoxicol Environ Saf, 2026-09-08)。 To evaluate the association between di(2-ethylhexyl) phthalate (DEHP) exposure and testosterone deficiency in adult men, and to explore molecular changes and candidate compounds related to DEHP-associ…

推荐理由

男科相关相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-08Curr Opin UrolJournal Article仅摘要JCR Q2
Epigenomics in severe male infertility: sperm-derived cell-free DNA methylation for prediction of sperm retrieval.

聚焦男性不育方向(Curr Opin Urol, 2026-09-08)。 Severe male factor infertility is increasingly managed with surgical sperm retrieval, yet current noninvasive predictors cannot reliably distinguish men with retrievable focal spermatogenesis from tho…

推荐理由

男性不育相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-08Arch Ital Urol AndrolJournal Article仅摘要JCR Q3
Sleep disorders and male sexual dysfunction: a meta-analysis of hormonal and erectile outcomes.

聚焦勃起功能障碍(ED)方向(Arch Ital Urol Androl, 2026-09-08)。 Sleep disruptions, including insomnia and obstructive sleep apnea (OSA), are strongly linked to male sexual dysfunction, affecting libido, erectile function, and hormonal balance. This metaanalysis ai…

推荐理由

勃起功能障碍(ED)相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-08Cancer Treat Res CommunJournal Article仅摘要JCR Q2
Integrative transcriptomic identification of potential common biomarkers between non-obstructive azoospermia and papillary thyroid cancer via multi-algorithmic machine learning and network biology approaches.

聚焦无精子症方向(Cancer Treat Res Commun, 2026-09-08)。 Emerging evidence suggests potential mechanistic links between non-obstructive azoospermia (NOA) and papillary thyroid carcinoma (PTC) through shared signaling pathways. However, no integrative transc…

推荐理由

无精子症相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

2026-09-07 星期一 · 当天 3 条
来源:PubMed(按真实发表日,非收录日)· 每条附 PMID 可核对 · 期刊标注 JCR 分区(Q1–Q4,2024 JCR / 2025-06 发布,SJR 核实)
09-07Comp Biochem Physiol Part D Genomics ProteomicsJournal Article仅摘要JCR Q1
Multi-omics analysis reveals molecular disruption in mouse testes following cumulative heat stress.

聚焦男科相关方向(Comp Biochem Physiol Part D Genomics Proteomics, 2026-09-07)。 Rising global temperatures threaten male fertility, yet the molecular mechanisms by which heat stress disrupts spermatogenesis remain incompletely understood. We employed an integrative multi-omics ap…

推荐理由

男科相关相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-07J UrolJournal Article仅摘要JCR Q1
Male Infertility.

聚焦男性不育方向(J Urol, 2026-09-07)。

推荐理由

男性不育相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-07J Obstet Gynaecol CanJournal Article仅摘要JCR Q2
The Impact of Government-Funded In Vitro Fertilization on the Use of Intracytoplasmic Sperm Injection in Non-Male Factor Infertility.

聚焦男性不育方向(J Obstet Gynaecol Can, 2026-09-07)。 To evaluate the impact of Ontario's public in vitro fertilization (IVF) funding program on intracytoplasmic sperm injection (ICSI) use and reproductive outcomes in non-male factor infertility (NMFI),…

推荐理由

男性不育相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

2026-09-06 星期日 · 当天 3 条
来源:PubMed(按真实发表日,非收录日)· 每条附 PMID 可核对 · 期刊标注 JCR 分区(Q1–Q4,2024 JCR / 2025-06 发布,SJR 核实)
09-06Comp Biochem Physiol Part D Genomics ProteomicsJournal Article仅摘要JCR Q1
Proteomic and functional characterization of seminal and epididymal plasma proteins associated with male fertility in cattle: A comprehensive review.

聚焦精液/精液组学方向(Comp Biochem Physiol Part D Genomics Proteomics, 2026-09-06)。 The animal industry is associated with substantial economic losses due to infertility and subfertility, with male infertility being a major contributing factor to breeding failure. Studies in cattle h…

推荐理由

精液/精液组学相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-06Global Spine JJournal ArticleOA全文JCR Q1
Testosterone Replacement Therapy is Associated With Increased Risk of Pseudarthrosis After Single-Level Anterior Cervical Discectomy and Fusion: A Propensity Matched Analysis.

聚焦性腺功能低下/睾酮方向(Global Spine J, 2026-09-06)。 ObjectiveTo evaluate whether preoperative testosterone replacement therapy (TRT) use is associated with increased risks of pseudarthrosis and reoperation following single-level anterior cervical disce…

推荐理由

性腺功能低下/睾酮相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-06Adv Healthc MaterJournal Article仅摘要JCR Q1
Seminiferous Tubules-Targeted Resveratrol Carbon Dots With Sertoli Cell Biomimetic Vesicles Fusion for Improving Spermatogenesis of Cryptorchidism.

聚焦精子发生/生精方向(Adv Healthc Mater, 2026-09-06)。 Impaired blood-testis barrier (BTB) integrity, induced by oxidative stress, is one of the primary factors leading to spermatogenic disorders in cryptorchidism. Therefore, the targeted elimination of t…

推荐理由

精子发生/生精相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

2026-09-05 星期六 · 当天 28 条
来源:PubMed(按真实发表日,非收录日)· 每条附 PMID 可核对 · 期刊标注 JCR 分区(Q1–Q4,2024 JCR / 2025-06 发布,SJR 核实)
09-05Asian J AndrolJournal Article仅摘要JCR Q2
Testicular sperm aspiration enhances fertilization rates in MMAF patients undergoing ICSI: a retrospective cohort study.

聚焦男科相关方向(Asian J Androl, 2026-09-05)。 Multiple morphological abnormalities of the sperm flagella (MMAF) compromise intracytoplasmic sperm injection (ICSI) outcomes. Testicular sperm aspiration (TESA) may be beneficial, but its impact on e…

推荐理由

男科相关相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-05Asian J AndrolJournal Article仅摘要JCR Q2
The causal effect of family history of cardiovascular disease on erectile dysfunction: a randomized clinical study and Mendelian randomization study.

聚焦勃起功能障碍(ED)方向(Asian J Androl, 2026-09-05)。 Erectile dysfunction (ED) is increasingly recognized as an early clinical marker of cardiovascular disease (CVD); however, the causal role of familial predisposition to CVD in ED development remains i…

推荐理由

勃起功能障碍(ED)相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-05Asian J AndrolJournal Article仅摘要JCR Q2
Differences in adipose-derived stem cells from rats with various health statuses and their effects in diabetic rats with erectile dysfunction.

聚焦勃起功能障碍(ED)方向(Asian J Androl, 2026-09-05)。 It is essential to use high-quality adipose-derived stem cells (ADSCs) for clinical applications. The functional characteristics of ADSCs differ in the presence of various health conditions. Specifica…

推荐理由

勃起功能障碍(ED)相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-05CryobiologyJournal Article仅摘要JCR Q2
An effective strategy for rare microdissection testicular sperm involves utilizing a micro-cryopreservation technique combined with laser-assisted selection of immotile sperm after thawing.

聚焦男科相关方向(Cryobiology, 2026-09-05)。 The challenge with spermatozoa retrieval in non-obstructive azoospermia (NOA) patients is that testicular spermatozoa are frequently immotile and exceedingly scarce. The cryopreservation of these limi…

推荐理由

男科相关相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-05Asian J AndrolJournal Article仅摘要JCR Q2
Outcomes following varicocele treatment: a comparative study of microsurgical and angioembolization approaches.

聚焦精索静脉曲张方向(Asian J Androl, 2026-09-05)。 The aim of this study was to compare outcomes of microsurgical varicocelectomy (MV) versus percutaneous angioembolization (AE) in men with varicoceles causing infertility or scrotal pain. Endpoints in…

推荐理由

精索静脉曲张相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-05Asian J AndrolJournal Article仅摘要JCR Q2
A novel hemizygous missense variant in the BEND2 gene is associated with nonobstructive azoospermia.

聚焦无精子症方向(Asian J Androl, 2026-09-05)。 Nonobstructive azoospermia (NOA), the most severe form of male infertility, frequently arises from genetic defects that disrupt spermatogenesis. In this study, a novel hemizygous missense variant (NM_…

推荐理由

无精子症相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-05Asian J AndrolJournal Article仅摘要JCR Q2
Proteomic insights into azoospermia: protein differences in testicular tissue between non-obstructive and obstructive azoospermia patients.

聚焦无精子症方向(Asian J Androl, 2026-09-05)。 Non-obstructive azoospermia (NOA) and obstructive azoospermia (OA) are the main classifications of severe male infertility, but the molecular mechanism of NOA remains poorly understood. This study aim…

推荐理由

无精子症相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-05Asian J AndrolJournal Article仅摘要JCR Q2
Effects and mechanism of low-intensity pulsed ultrasounds on testicular steroidogenesis in rats.

聚焦男科相关方向(Asian J Androl, 2026-09-05)。 Low-intensity pulsed ultrasound (LIPUS) has emerged as a non-invasive therapeutic approach with regenerative potential in various tissues. This study explores its effects on testicular steroidogenesis…

推荐理由

男科相关相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-05Asian J AndrolJournal Article仅摘要JCR Q2
Surgical treatment of Peyronie's disease by plaque incision and buccal mucosa graft: a systematic review and meta-analysis.

聚焦Peyronie病/阴茎弯曲方向(Asian J Androl, 2026-09-05)。 Peyronie's disease (PD) is a debilitating condition affecting the sexual and psychological health of millions of men and their partners around the world. Plaque incision (PI) surgery with buccal mucos…

推荐理由

Peyronie病/阴茎弯曲相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-05Asian J AndrolJournal Article仅摘要JCR Q2
Association between body mass index and semen quality in infertile men: a cross-sectional study of 28 167 patients.

聚焦精液/精液组学方向(Asian J Androl, 2026-09-05)。 Although the detrimental impact of abnormal body mass index (BMI) on semen quality is well established in the general population, studies exploring this relationship in infertile men remain limited. T…

推荐理由

精液/精液组学相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-05Asian J AndrolJournal Article仅摘要JCR Q2
Fresh or frozen testicular sperm? Guidance from an etiology-classified retrospective study on ICSI cycles for patients with azoospermia.

聚焦无精子症方向(Asian J Androl, 2026-09-05)。 Using testicular sperm, men with azoospermia can father children. Sperm cryopreservation helps avoid the risk of cycle canceling because of the failure of testicular sperm retrieval. However, cryopres…

推荐理由

无精子症相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-05Asian J AndrolJournal Article仅摘要JCR Q2
Psychological and sexual associations of azoospermia in men: a cross-sectional pre-biopsy study.

聚焦无精子症方向(Asian J Androl, 2026-09-05)。 Azoospermia can lead to significant psychological distress, low self-esteem, and compromised sexual function. However, the impact of these issues before any invasive diagnostic or treatment procedures…

推荐理由

无精子症相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-05Asian J AndrolJournal Article仅摘要JCR Q2
The therapeutic effect and mechanism of low-intensity pulsed ultrasound for erectile dysfunction.

聚焦勃起功能障碍(ED)方向(Asian J Androl, 2026-09-05)。 As an emerging therapeutic option for erectile dysfunction (ED), low-intensity pulsed ultrasound (LIPUS) has attracted increasing attention. The therapeutic effect of LIPUS is comparable to low-intens…

推荐理由

勃起功能障碍(ED)相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-05Asian J AndrolJournal Article仅摘要JCR Q2
Correlation between weight loss and testosterone restoration after sleeve gastrectomy in patients with biochemical male obesity-associated secondary hypogonadism.

聚焦性腺功能低下/睾酮方向(Asian J Androl, 2026-09-05)。 Male obesity-associated secondary hypogonadism (MOSH) affects metabolic and reproductive health. We evaluated the efficacy of laparoscopic sleeve gastrectomy (LSG) on the remission of MOSH and testost…

推荐理由

性腺功能低下/睾酮相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-05Asian J AndrolJournal Article仅摘要JCR Q2
Prevalence of semen abnormalities and the impact of genital pathogens on male infertility: a retrospective analysis of 131 183 patients.

聚焦男性不育方向(Asian J Androl, 2026-09-05)。 Infertility affects approximately 15% of couples of reproductive age worldwide, with male factors contributing to nearly 40%-50% of cases. Because semen quality is a fundamental indicator of male fert…

推荐理由

男性不育相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-05Asian J AndrolJournal Article仅摘要JCR Q2
Combined effects of urine exposure and cryopreservation on sperm quality: an in vitro study of retrograde ejaculation.

聚焦男科相关方向(Asian J Androl, 2026-09-05)。 Sperm quality influences fertility and offspring health through both genomic inheritance and epigenetic inheritance. Thus, for use in clinical-assisted reproductive technology (ART), spermatozoa must…

推荐理由

男科相关相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-05Asian J AndrolJournal Article仅摘要JCR Q2
Loss-of-function mutations in Ccdc113 cause male infertility in both humans and mice.

聚焦男性不育方向(Asian J Androl, 2026-09-05)。 Although genetic factors contribute significantly to male infertility, the underlying mechanisms remain incompletely understood. Coiled-coil domain-containing protein 113 ( CCDC113 ) encodes a coiled-…

推荐理由

男性不育相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-05CryobiologyJournal Article仅摘要JCR Q2
Protective effects of seminal exosomes on cryopreserved sperm via inhibiting oxidative damage.

聚焦精液/精液组学方向(Cryobiology, 2026-09-05)。 This study aimed to explore the protective effect of seminal plasma exosomes (SPEs) on human sperm structure and function during cryopreservation and its potential mechanism. The samples were divided…

推荐理由

精液/精液组学相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-05Asian J AndrolJournal Article仅摘要JCR Q2
Association of Ureaplasma urealyticum with lifestyle factors and semen parameters: results from a cross-sectional study in 2668 males.

聚焦精液/精液组学方向(Asian J Androl, 2026-09-05)。 Lifestyle factors have been linked to decreased sperm quality and may influence the prevalence of Ureaplasma urealyticum infection. This study aims to clarify the relationships among Ureaplasma urealy…

推荐理由

精液/精液组学相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-05Asian J AndrolJournal Article仅摘要JCR Q2
Predictive factors shaping fertility potential and reproductive outcomes in men with Klinefelter syndrome.

聚焦Klinefelter综合征方向(Asian J Androl, 2026-09-05)。 Klinefelter syndrome (KS), marked by testicular heterogeneity, provides a rationale for testicular sperm extraction in azoospermic men, yet large-scale evaluations of predictive and reproductive outco…

推荐理由

Klinefelter综合征相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-05Asian J AndrolJournal Article仅摘要JCR Q2
Novel biallelic FSIP2 variants cause male infertility with multiple morphological abnormalities of sperm flagella in humans.

聚焦男性不育方向(Asian J Androl, 2026-09-05)。 Biallelic variants in fibrous sheath-interacting protein 2 ( FSIP2 ) gene are a known cause of multiple morphological abnormalities of the sperm flagella (MMAF). This study aimed to identify novel FSI…

推荐理由

男性不育相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-05Clin Med Insights Arthritis Musculoskelet DisordJournal ArticleOA全文JCR Q3
Associated Determinants of Sexual Dysfunctions in Non-Specific Low Back Pain Patients in Cameroon: A Cross-Sectional Study.

聚焦性健康/性心理方向(Clin Med Insights Arthritis Musculoskelet Disord, 2026-09-05)。 Non-specific low back pain (NSLBP) is a significant factor involved in the onset of sexual dysfunctions (SDs). However, studies demonstrating the correlation between these 2 conditions are rare. This…

推荐理由

性健康/性心理相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-05Medicine (Baltimore)Journal ArticleOA全文JCR Q2
Feasibility of laparoscopic radical prostatectomy initiation by a surgeon with limited open surgery experience: A single-surgeon series with prior laparoscopic background.

聚焦前列腺方向(Medicine (Baltimore), 2026-09-05)。 Due to its greater accessibility and cost-effectiveness, laparoscopic radical prostatectomy (LRP) is widely preferred worldwide. The aim of this study was to evaluate the outcomes of laparoscopy perfo…

推荐理由

前列腺相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-05ToxicologyJournal Article仅摘要JCR Q1
Sodium valproate at concentrations bracketing estimated seminal plasma levels impairs human sperm function in vitro through oxidative stress and mitochondrial dysfunction.

聚焦精液/精液组学方向(Toxicology, 2026-09-05)。 Sodium valproate (VPA), a first-line broad-spectrum antiseizure medication, has been associated with altered semen quality in clinical settings, but its direct effects on human sperm remain incomplete…

推荐理由

精液/精液组学相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-05J Hum GenetJournal ArticleOA全文JCR Q2
Biallelic nonsense variants in GAS8 associated with asthenoteratozoospermia and PCD-like symptoms.

聚焦畸精症方向(J Hum Genet, 2026-09-05)。 We report a 28-year-old infertile male presenting with markedly reduced progressive sperm motility and severe morphological abnormalities (normal morphology rate: 1%), accompanied by primary ciliary d…

推荐理由

畸精症相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-05AndrologyJournal Article仅摘要JCR Q1
Long-Term Satisfaction With Inflatable Penile Prosthesis Using the Satisfaction Survey for Inflatable Penile Implant in a Veteran Population.

聚焦阴茎/假体方向(Andrology, 2026-09-05)。 Inflatable penile prosthesis (IPP) is the gold standard for refractory erectile dysfunction, yet long-term outcomes in the Veterans Affairs (VA) health care population remain incompletely characterize…

推荐理由

阴茎/假体相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-05AndrologyJournal Article仅摘要JCR Q1
Electroacupuncture at SP6 Modulates Functional Brain Networks and Reduces Plasma Norepinephrine to Ameliorate Premature Ejaculation in Rats.

聚焦早泄方向(Andrology, 2026-09-05)。 The brain plays a critical role in premature ejaculation (PE), but the specific regions involved remain unclear. This study aimed to identify functional brain network alterations in PE-like rats and i…

推荐理由

早泄相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

2026-09-04 星期五 · 当天 7 条
来源:PubMed(按真实发表日,非收录日)· 每条附 PMID 可核对 · 期刊标注 JCR 分区(Q1–Q4,2024 JCR / 2025-06 发布,SJR 核实)
09-04PhytomedicineJournal Article仅摘要JCR Q1
Total glycosides of Cistanche deserticola ameliorate alcohol-induced oligoasthenozoospermia via the modulation of gut microbiota-mediated spermidine metabolism.

聚焦少弱畸精症方向(Phytomedicine, 2026-09-04)。 Oligoasthenozoospermia is a major cause of male infertility, with chronic excessive alcohol consumption being a prevalent etiology. Cistanche deserticola Ma., a traditional Chinese medicine historical…

推荐理由

少弱畸精症相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-04J Sex MedJournal Article仅摘要JCR Q1
Unmet needs in the treatment of erectile dysfunction and a place for topical treatments in the therapeutic landscape.

聚焦勃起功能障碍(ED)方向(J Sex Med, 2026-09-04)。 Systemic therapy with phosphodiesterase type 5 inhibitors (PDE5is) is the standard of care for erectile dysfunction (ED), but these treatments are not effective in all men, and others may prefer non-s…

推荐理由

勃起功能障碍(ED)相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-04F S SciJournal Article仅摘要JCR Q2
Deoxyribonucleic acid methylation abnormalities at imprinted loci in oligospermic and azoospermic men.

聚焦无精子症方向(F S Sci, 2026-09-04)。 To assess deoxyribonucleic acid (DNA) methylation at imprinted and repetitive genomic regions in ejaculated and testicular sperm from men with oligospermia, azoospermia, and those undergoing vasectomy…

推荐理由

无精子症相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-04Eur Urol FocusJournal Article仅摘要JCR Q1
Blue Laser Vaporization for Benign Prostatic Hyperplasia: A Prospective Cohort Study on Efficacy and Preservation of Ejaculation.

聚焦男科相关方向(Eur Urol Focus, 2026-09-04)。 Surgical treatments for benign prostatic hyperplasia (BPH) often impair sexual function. The 450&#xa0;nm blue laser, with its high hemoglobin absorption and shallow penetration, offers rapid tissue va…

推荐理由

男科相关相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-04UrologiaJournal Article仅摘要JCR Q3
Surgical sperm retrieval in cases with non obstructive azoospermia, comparative study between maldescended and normal positioned testis.

聚焦无精子症方向(Urologia, 2026-09-04)。 Non-obstructive azoospermia (NOA) is absent sperm due to defective spermatogenesis from causes like cryptorchidism, genetics, or unknown factors.

推荐理由

无精子症相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

2026-09-03 星期四 · 当天 34 条
来源:PubMed(按真实发表日,非收录日)· 每条附 PMID 可核对 · 期刊标注 JCR 分区(Q1–Q4,2024 JCR / 2025-06 发布,SJR 核实)
09-03AndrologyJournal ArticleOA全文JCR Q1
Smooth Muscle Cell-Derived Exosomal miR-30a-5p as a Novel Therapeutic Strategy for Erectile Dysfunction in Diabetes Mellitus.

聚焦勃起功能障碍(ED)方向(Andrology, 2026-09-03)。 Erectile dysfunction (ED) affects more than half of male patients with diabetes. Diabetes mellitus-related ED (DMED) remains challenging to manage due to hyperglycemia-induced apoptosis and fibrosis o…

推荐理由

勃起功能障碍(ED)相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-03AndrologyJournal ArticleOA全文JCR Q1
Testis-Enriched F-Box Protein FBXO39 Is Important for Spermiogenesis and Male Fertility in Mice.

聚焦睾丸/生精方向(Andrology, 2026-09-03)。 The SCF (Skp-Cullin-F-box) complex is a major class of E3 ubiquitin ligases. F-box proteins constitute the SCF complex and play a critical role in recognizing substrates for ubiquitination. In mice, s…

推荐理由

睾丸/生精相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-03AndrologyJournal ArticleOA全文JCR Q1
Variants in ZZS Complex-Associated Genes TEX11 and M1AP Are Responsible for Male Infertility and Nonobstructive Azoospermia.

聚焦无精子症方向(Andrology, 2026-09-03)。 Nonobstructive azoospermia (NOA) is the most severe form of male infertility, with genetic factors contributing to approximately 30% of cases. However, only a small fraction of all NOA cases can be ex…

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无精子症相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-03AndrologyJournal ArticleOA全文JCR Q1
USP2 Attenuates Spermatogenic Cell Apoptosis Via PINK1/Parkin-Dependent Mitophagy in Varicocoele: A Functional Study.

聚焦精子发生/生精方向(Andrology, 2026-09-03)。 Varicocoele is a major cause of male infertility, yet its underlying molecular mechanisms and determinants of surgical efficacy remain unclear.

推荐理由

精子发生/生精相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-03AndrologyJournal ArticleOA全文JCR Q1
Slit2/Robo Signaling Restores Diabetic Erectile Function via Neurovascular Remodeling.

聚焦勃起功能障碍(ED)方向(Andrology, 2026-09-03)。 Diabetes mellitus-induced erectile dysfunction (DMED) is a common and debilitating vascular-neurogenic complication of diabetes. The poor responsiveness of DMED patients to phosphodiesterase type-5 in…

推荐理由

勃起功能障碍(ED)相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-03AndrologyJournal ArticleOA全文JCR Q1
Cyclic Treatment With WIN 18,446, a Potential Male Contraceptive, is as Effective as Continuous Treatment for Suppression of Spermatogenesis in Mice.

聚焦精子发生/生精方向(Andrology, 2026-09-03)。 Retinoic acid plays a critical role in spermatogenesis during both spermatogonial differentiation and spermiation. Mice lacking enzymes that synthesize retinoic acid, Aldh1a1/1a2, in the testes are in…

推荐理由

精子发生/生精相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-03AndrologyJournal ArticleOA全文JCR Q1
Unraveling the Pathways Linking Sleep Disturbance and Vasculogenic Erectile Dysfunction: The Dominant Role of Inflammation and Testosterone Mediation.

聚焦勃起功能障碍(ED)方向(Andrology, 2026-09-03)。 Poor sleep quality is associated with erectile dysfunction (ED), but the underlying mechanisms remain unclear. Given that systemic inflammation and testosterone levels are key factors in vascular heal…

推荐理由

勃起功能障碍(ED)相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-03AndrologyJournal ArticleOA全文JCR Q1
Comprehensive Quantification of Oligoasthenozoospermia Induced by Obesity, Reproductive Toxicants, and Their Combination in Rat Models.

聚焦少弱畸精症方向(Andrology, 2026-09-03)。 Oligoasthenozoospermia is a leading cause of male infertility and has been increasingly associated with the global surge in obesity and exposure to reproductive toxicants. Despite extensive research o…

推荐理由

少弱畸精症相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-03AndrologyJournal ArticleOA全文JCR Q1
Comparison of Different Sperm Isolation Strategies for Fresh and Cryopreserved Human Spermatozoa Using a Simple Method for Simultaneously Assessing Sperm Vitality and DNA Fragmentation.

聚焦精子/精液方向(Andrology, 2026-09-03)。 This study compares three different methods of sperm isolation using a novel laboratory test that permits the parallel assessment of vitality and DNA integrity in the same sperm cell.

推荐理由

精子/精液相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-03AndrologyJournal ArticleOA全文JCR Q1
Low Free Testosterone Is Independently Associated With Long-Term Mortality in Men With Chronic Spinal Cord Injury.

聚焦性腺功能低下/睾酮方向(Andrology, 2026-09-03)。 Testosterone deficiency is highly prevalent in men with chronic spinal cord injury (SCI) and is associated with obesity, sarcopenia, systemic inflammation, and metabolic dysfunction. However, the inde…

推荐理由

性腺功能低下/睾酮相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-03AndrologyJournal ArticleOA全文JCR Q1
Artificial Intelligence in Patient Education: ChatGPT for Penile Prosthesis Surgery Counseling, a Likert Scale Analysis.

聚焦阴茎/假体方向(Andrology, 2026-09-03)。 Erectile dysfunction (ED) significantly impacts quality of life. For patients unresponsive to conservative treatments, penile prosthesis implantation represents an effective solution with high satisfa…

推荐理由

阴茎/假体相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-03AndrologyJournal ArticleOA全文JCR Q1
Oxidative Stress and its Implications for Male Reproductive Dysfunction: Mechanistic Insights, Clinical Impacts, and Advances in Therapeutic Interventions.

聚焦男科相关方向(Andrology, 2026-09-03)。 Oxidative stress (OS) significantly contributes to male reproductive dysfunction, a factor implicated in a substantial fraction of infertility cases. This comprehensive review elucidates the intricate…

推荐理由

男科相关相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-03AndrologyJournal ArticleOA全文JCR Q1
Penile Hemodynamic Patterns Highlighting the Impact of Diabetes in Young Men With Erectile Dysfunction.

聚焦勃起功能障碍(ED)方向(Andrology, 2026-09-03)。 Erectile dysfunction (ED) in young men is often assumed to be psychogenic, which may lead to underdiagnosis of organic causes such as vasculogenic ED, particularly in the absence of overt comorbiditie…

推荐理由

勃起功能障碍(ED)相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-03AndrologyJournal ArticleOA全文JCR Q1
Online Andrology: Real-World Status Quo of Patients' Online Information Sources and Comparison With Large Language Models in Germany.

聚焦男科学方向(Andrology, 2026-09-03)。 The internet, including websites and large language models (LLMs), is an increasingly important information resource for medical patients. However, information quality varies, potentially leading to m…

推荐理由

男科学相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-03Reprod Biomed OnlineJournal Article仅摘要JCR Q1
Evolutionary and epigenetic drivers of the global trajectory of sperm count decline: an integrative framework for male reproductive health.

聚焦男科相关方向(Reprod Biomed Online, 2026-09-03)。 Global meta-analyses have documented a decline in sperm concentration of approximately 50% since the 1970s, with rates accelerating from 1.16% to 2.64% annually. A parallel decline in serum testostero…

推荐理由

男科相关相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-03Hum Reprod UpdateJournal ArticleOA全文JCR Q1
Iron overload disorders in adults: a comprehensive review of gonadal function, reproductive, and sexual health.

聚焦性健康/性心理方向(Hum Reprod Update, 2026-09-03)。 Iron overload (IO) disorders, including thalassaemias, hereditary haemochromatosis, and transfusion-dependent anaemias, represent a growing clinical challenge with widespread systemic implications. Re…

推荐理由

性健康/性心理相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-03AndrologyJournal ArticleOA全文JCR Q1
Testicular SIRT1 Loss Reveals an Aging-Like Proteomic Landscape and Precipitates Reproductive Deterioration.

聚焦男科相关方向(Andrology, 2026-09-03)。 Advanced paternal age is associated with reduced male fertility and testicular dysfunction. Among the molecular regulators involved in aging, SIRT1, a NAD+-dependent deacetylase, plays a pivotal role…

推荐理由

男科相关相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-03AndrologyJournal ArticleOA全文JCR Q1
Pharmacologic and Nutritional Therapies in Idiopathic Male Infertility: A Systematic Review and Meta-Analysis.

聚焦男性不育方向(Andrology, 2026-09-03)。 Pharmacologic and nutritional therapies are prescribed for men with idiopathic infertility, but their effectiveness by intervention class remains uncertain.

推荐理由

男性不育相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-03AndrologyJournal ArticleOA全文JCR Q1
Preoperative Total Testicular Volume as a Predictor of Total Motile Sperm Count Improvement Following Microsurgical Varicocelectomy.

聚焦精索静脉曲张方向(Andrology, 2026-09-03)。 Varicocelectomy has been shown to improve semen parameters in men with infertility; however, not all men experience improvement. Identifying preoperative predictors of semen parameter improvement is n…

推荐理由

精索静脉曲张相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-03AndrologyJournal ArticleOA全文JCR Q1
A Systematic Review on Administration of Botulinum Toxin in the Management of Male Sexual Dysfunctions.

聚焦性健康/性心理方向(Andrology, 2026-09-03)。 Male sexual dysfunctions (SDs) like erectile dysfunction (ED), premature ejaculation (PE), and Peyronie's disease (PD) are highly prevalent conditions affecting the quality of life of men and their pa…

推荐理由

性健康/性心理相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-03AndrologyJournal ArticleOA全文JCR Q1
Can Hormonal Therapy Improve the Outcomes of mTESE in Patients With Non-Obstructive Azoospermia?

聚焦无精子症方向(Andrology, 2026-09-03)。 Non-obstructive azoospermia (NOA) represents the most severe form of male infertility. Hypogonadism is common in NOA patients, and normal testosterone (T) levels are considered essential for spermatog…

推荐理由

无精子症相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-03Ann Gastroenterol SurgJournal ArticleOA全文JCR Q1
Exploratory Analysis of Factors Associated With the Recovery of Erectile Dysfunction After Rectal Cancer Surgery (Sub-Analysis of LANDMARC Trial).

聚焦勃起功能障碍(ED)方向(Ann Gastroenterol Surg, 2026-09-03)。 Erectile dysfunction (ErD) is an important complication after rectal cancer surgery, however a substantial proportion of patients experience functional recovery over time. Evidence regarding which pat…

推荐理由

勃起功能障碍(ED)相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-03AndrologyJournal ArticleOA全文JCR Q1
ClpP Ensures Mitochondrial Integrity and Spermatocyte Meiotic Progression in Mice.

聚焦男科相关方向(Andrology, 2026-09-03)。 Caseinolytic peptidase P (ClpP) plays a key role in maintaining cellular homeostasis for mitochondrial quality control. However, the specific function of ClpP during meiosis and its subcellular locali…

推荐理由

男科相关相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-03AndrologyJournal ArticleOA全文JCR Q1
Expression of miR-339-3p and OPRM1 in relation to sperm function in male infertility.

聚焦男性不育方向(Andrology, 2026-09-03)。 Infertility is the inability of a couple to conceive after 12 months of unprotected intercourse. The &#xb5;-opioid receptor involved in mediating opioid effects and may be associated with male fertili…

推荐理由

男性不育相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-03AndrologyJournal ArticleOA全文JCR Q1
Semen Quality in Transgender Individuals Seeking Fertility Preservation.

聚焦精液/精液组学方向(Andrology, 2026-09-03)。 Transgender individuals assigned male at birth (AMAB) may choose to preserve their fertility prior to starting gender-affirming hormone therapy (GAHT). However, limited data exist regarding the baseli…

推荐理由

精液/精液组学相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-03AndrologyJournal ArticleOA全文JCR Q1
Association Between Isolated Postprandial Dyslipidemia And Erectile Dysfunction.

聚焦勃起功能障碍(ED)方向(Andrology, 2026-09-03)。 Postprandial lipid testing is increasingly recognized as a marker of vascular health. However, its relationship with erectile dysfunction (ED) remains largely unexplored. Isolated postprandial dyslipi…

推荐理由

勃起功能障碍(ED)相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-03J Clin PsychiatryJournal Article仅摘要JCR Q1
Evaluation of Sexual Function With Adjunctive Lumateperone in Patients With Major Depressive Disorder.

聚焦性健康/性心理方向(J Clin Psychiatry, 2026-09-03)。 Objective: Lumateperone is an atypical antipsychotic to treat schizophrenia, bipolar I or II depression, and major depressive disorder (MDD). Randomized phase 3 Study 502 (NCT05061706) investigated th…

推荐理由

性健康/性心理相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-03Int J Impot ResJournal ArticleOA全文JCR Q3
The management of non-infectious complications of penile implant surgery-a narrative review.

聚焦阴茎/假体方向(Int J Impot Res, 2026-09-03)。 Penile implant surgery is a well-established treatment for erectile dysfunction. While patient and partner satisfaction rates are high, any non-infectious complication can significantly affect functio…

推荐理由

阴茎/假体相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-03AndrologyJournal Article仅摘要JCR Q1
Altered Functional Coherence of the Right Anterior Insula in Men With Nonorganic Erectile Dysfunction: A Resting-State fMRI Study.

聚焦勃起功能障碍(ED)方向(Andrology, 2026-09-03)。 Nonorganic erectile dysfunction (nonorganic ED) is a common subtype of ED characterized by impaired erectile function in the absence of identifiable organic causes. Although ED is increasingly recogni…

推荐理由

勃起功能障碍(ED)相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-03GesundheitswesenEnglish Abstract仅摘要JCR Q3
[WHO Guideline for the prevention, diagnosis and treatment of infertility].

聚焦男性不育方向(Gesundheitswesen, 2026-09-03)。 Infertility affects approximately one in six people of reproductive age worldwide and represents a major global health issue, regardless of world region or income level. It limits the realization of i…

推荐理由

男性不育相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-03J Clin Endocrinol MetabJournal Article仅摘要JCR Q1
Assessment of testicular function in boys with hematological malignancies: a prospective longitudinal study.

聚焦男科相关方向(J Clin Endocrinol Metab, 2026-09-03)。 Survival after pediatric hematologic malignancies has improved substantially, increasing concern regarding endocrine sequelae. While gonadotoxic effects on germ cells are characterized in adult surviv…

推荐理由

男科相关相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-03J HeredJournal Article仅摘要JCR Q1
Ex situ reared black-footed ferrets exhibit altered sperm DNA methylation.

聚焦男科相关方向(J Hered, 2026-09-03)。 Many endangered species rely on ex situ management for survival when external threats exist on the landscape. Yet, ex situ settings pose challenges through space limitation, altered environment, and d…

推荐理由

男科相关相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-03Anat Cell BiolJournal Article仅摘要JCR Q2
Moringa leaf mitigates 4G cell phone radiation-induced alterations in testicular histomorphometry and spermatogenesis during sexual maturation in Wistar rats.

聚焦精子发生/生精方向(Anat Cell Biol, 2026-09-03)。 The use of android phones is alarmingly increasing among the late juvenile and adolescent population. The infertility results from the detrimental effects of cell phone electromagnetic radiation (EMR)…

推荐理由

精子发生/生精相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

2026-09-02 星期三 · 当天 7 条
来源:PubMed(按真实发表日,非收录日)· 每条附 PMID 可核对 · 期刊标注 JCR 分区(Q1–Q4,2024 JCR / 2025-06 发布,SJR 核实)
09-02J Endocr SocJournal ArticleOA全文JCR Q2
Association of testosterone and testosterone replacement therapy with atrial fibrillation: an updated review.

聚焦性腺功能低下/睾酮方向(J Endocr Soc, 2026-09-02)。 Historically, low testosterone (T) has been linked to increased atrial fibrillation (AF) risk in men, yet recent evidence suggests that elevated T levels and testosterone replacement therapy (TRT) may…

推荐理由

性腺功能低下/睾酮相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-02Reprod SciJournal ArticleOA全文JCR Q1
Obeticholic Acid Rescues Male Reproductive Function in High-Fat Diet-Induced Metabolic Syndrome.

聚焦男科相关方向(Reprod Sci, 2026-09-02)。 Metabolic syndrome (MetS) contributes to male infertility, yet the impact of MetS-targeted therapies on fertility remains unclear. This study investigates the impact of obeticholic acid (OCA), a farne…

推荐理由

男科相关相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-02Nat Rev UrolJournal ArticleOA全文JCR Q1
Sperm DNA fragmentation and its influence on mammalian reproduction.

聚焦男科相关方向(Nat Rev Urol, 2026-09-02)。 Sperm DNA fragmentation is a recognized factor in male infertility with direct implications for embryo development, implantation and pregnancy outcomes. Historically, standard semen analysis has not i…

推荐理由

男科相关相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-02Int J Food Sci NutrJournal Article仅摘要JCR Q1
Nutraceutical administration targeting energy metabolism and antioxidant defences improves spermiogram and biochemical quality of seminal plasma of infertile males in a pilot study.

聚焦精液/精液组学方向(Int J Food Sci Nutr, 2026-09-02)。 Pre- and post-intervention spermiogram analysis and high-performance liquid chromatography (HPLC) profiling of fat- and water-soluble seminal plasma (SP) metabolites were performed in 26 infertile men…

推荐理由

精液/精液组学相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-02AndrologyJournal Article仅摘要JCR Q1
Seminal Biomarkers and Sperm Proteomic Signatures Differentiate Acute and Chronic Male Accessory Gland Inflammation.

聚焦精液/精液组学方向(Andrology, 2026-09-02)。 Male accessory gland inflammation (MAGI) comprises a heterogeneous group of inflammatory conditions that may differentially affect the seminal microenvironment and sperm function. However, whether tra…

推荐理由

精液/精液组学相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

09-02Reprod BiolJournal Article仅摘要JCR Q1
Altered expression of the ferroptosis-related lncRNA TUG1 correlates with impaired sperm motility in asthenozoospermic men.

聚焦男科相关方向(Reprod Biol, 2026-09-02)。 Asthenozoospermia, a common cause of male infertility characterized by reduced sperm motility, has been linked to oxidative stress and ferroptosis. Long non-coding RNAs (lncRNAs) are emerging regulato…

推荐理由

男科相关相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

2026-09-01 星期二 · 当天 1 条
来源:PubMed(按真实发表日,非收录日)· 每条附 PMID 可核对 · 期刊标注 JCR 分区(Q1–Q4,2024 JCR / 2025-06 发布,SJR 核实)
09-01Ultrasound Med BiolJournal Article仅摘要JCR Q1
Value of Testicular Shear Wave Dispersion Imaging in Predicting Semen Improvement After Varicocelectomy.

聚焦精索静脉曲张方向(Ultrasound Med Biol, 2026-09-01)。 To evaluate the value of testicular viscoelastic parameters in predicting the improvement of semen parameters after varicocelectomy through testicular shear wave dispersion imaging.

推荐理由

精索静脉曲张相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

2026-08-31 星期一 · 当天 7 条
来源:PubMed(按真实发表日,非收录日)· 每条附 PMID 可核对 · 期刊标注 JCR 分区(Q1–Q4,2024 JCR / 2025-06 发布,SJR 核实)
08-31Int J Impot ResJournal ArticleOA全文JCR Q3
Perception and Reality of Postoperative Penile Length in Men Undergoing Plaque Excision and Grafting for Peyronie's Disease.

聚焦Peyronie病/阴茎弯曲方向(Int J Impot Res, 2026-08-31)。 Partial plaque excision and grafting (PEG) is the gold standard treatment for patients with severe Peyronie's Disease (PD) with preserved erectile function and deformity refractory to conservative man…

推荐理由

Peyronie病/阴茎弯曲相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

08-31Int J Impot ResJournal ArticleOA全文JCR Q3
The 50 most-cited primary studies in penile prosthesis surgery: An all-time bibliometric analysis.

聚焦阴茎/假体方向(Int J Impot Res, 2026-08-31)。 Penile prosthesis (PP) surgery represents a cornerstone intervention for erectile dysfunction (ED). Despite extensive literature, the most-cited primary studies across the full history of the field ha…

推荐理由

阴茎/假体相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

08-31Mol Cell BiochemJournal ArticleOA全文JCR Q1
USP35-mediated NRF2 deubiquitination attenuates experimental cryptorchidism-induced testicular damage and H2O2-induced apoptosis and oxidative stress in spermatogonia.

聚焦男科相关方向(Mol Cell Biochem, 2026-08-31)。 Cryptorchidism, characterized by the failure of one or both testes to descend into the scrotum, is the most prevalent urogenital malformation in male infants and an important risk element of male infe…

推荐理由

男科相关相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

08-31Biol ReprodJournal Article仅摘要JCR Q2
LncRNA THOR regulates spermatogenesis by interacting with and stabilizing Sycp3 protein in zebrafish.

聚焦精子发生/生精方向(Biol Reprod, 2026-08-31)。 THOR (testis-associated highly conserved oncogenic long non-coding RNA) is a highly conserved and testis-enriched lncRNA across vertebrates that plays diverse roles in various cancers. However, its ph…

推荐理由

精子发生/生精相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

08-31Hum ReprodJournal Article仅摘要JCR Q1
A Western-style diet exacerbates male infertility in M1ap knockout mice.

聚焦男性不育方向(Hum Reprod, 2026-08-31)。 What are the individual and combined effects of a common genetic cause of human male infertility (loss of M1AP function) and a negative lifestyle factor (a Western diet) on male fertility, spermatogen…

推荐理由

男性不育相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

08-31AndrologyJournal Article仅摘要JCR Q1
Prevalence of Spermatozoa in the Ejaculate of Adolescents With Klinefelter Syndrome: Implications for Fertility Counseling.

聚焦Klinefelter综合征方向(Andrology, 2026-08-31)。 Klinefelter syndrome (KS) is the most common genetic cause of male infertility and is associated with nonobstructive azoospermia. Advances in surgical sperm retrieval techniques have enabled biologica…

推荐理由

Klinefelter综合征相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

08-31World J UrolJournal ArticleOA全文JCR Q1
Pelvic floor muscle training for erectile function in men undergoing radical prostatectomy: a systematic review of randomized controlled trials.

聚焦勃起功能障碍(ED)方向(World J Urol, 2026-08-31)。 We aimed to evaluate the effectiveness of pelvic floor muscle training (PFMT), with or without adjunctive biofeedback or electrical stimulation, in improving erectile function (EF) in men who have und…

推荐理由

勃起功能障碍(ED)相关研究,对男科临床评估或治疗决策有参考价值,建议结合摘要与全文进一步判断。

2026-08-30 星期日 · 当天 3 条
来源:PubMed(按真实发表日,非收录日)· 每条附 PMID 可核对 · 期刊标注 JCR 分区(Q1–Q4,2024 JCR / 2025-06 发布,SJR 核实)
08-29Reprod ToxicolArticle仅摘要JCR Q2
Evaluation of the intergenerational effects of valproic acid and sodium butyrate on male reproductive parameters in the rat

以 10 或 20 mg/kg 丙戊酸(VPA)或钠丁酸盐(SB)处理雄性大鼠,评估对雄性生殖参数的跨代影响:VPA/SB 处理雄鼠使致孕能力、产仔数与窝重下降且持续两代;仅 VPA 组出现精子计数/活力/睾酮下降及附睾头/尾少精子症,且具跨代性。

推荐理由

量化了抗癫痫药 VPA 对雄性生殖的跨代损害(精子、睾酮、少精子症),为育龄男性癫痫患者用药与生育力保存咨询提供实验依据;SB 作为替代虽未显现相同精子参数损害但仍有跨代繁殖力下降,提示两药需分别评估。

08-28Clin BiochemLetter仅摘要JCR Q2
Implementing high-value testing: response to the VALOR-ED pathway

这是对本栏目 2026-08-29 已收录的 VALOR-ED 检验路径(针对 ED 与疑似性腺功能低下,提出表型验证—分析适用性—心血管代谢风险—选择性 reflex 检测—可行动报告五要素)的同行回应/实践评论,在高价值检测框架下讨论如何落实 ED 与性腺功能低下的实验室检测与价值论证。

推荐理由

路径类论文出现“回应—对话”,说明 VALOR-ED 框架正进入临床检验实践讨论,有助于推动 ED/性腺低下检测的规范化、与预防衔接及报销/价值论证,值得持续追踪其多中心验证进展。

08-25Pol Arch Intern MedCorrection仅摘要JCR Q1
Corrections: Erectile dysfunction and quality of life after myocardial infarction: a cross-sectional study with routine point-of-care penile Doppler ultrasonography

该文为对已发表横断面研究的勘误/更正声明,原研究在心肌梗死(MI)后患者中用常规床旁阴茎多普勒超声评估勃起功能障碍(ED)与生活质量;更正本身不提供新数据,但反映 MI 后 ED 客观评估(含多普勒)仍属活跃临床议题。

推荐理由

心血管—男科交叉领域,MI 后 ED 早期筛查与客观化评估(床旁多普勒)持续有发表活动;勘误提醒临床在 MI 后常规筛查 ED 并关注其作为心血管预后信号的价值。

2026-08-29 星期六 · 当天 15 条
来源:PubMed(按真实发表日,非收录日)· 每条附 PMID 可核对 · 期刊标注 JCR 分区(Q1–Q4,2024 JCR / 2025-06 发布,SJR 核实)
08-29J Assist Reprod GenetArticleOA全文JCR Q2
Biallelic FSIP2 variants are associated with sperm defective chromatin condensation beyond MMAF and acrosomal abnormalities

在携带 FSIP2 纯合变异的不育男性中系统刻画精子表型与生殖特征,发现除既往已知的 MMAF(多发鞭毛形态异常)与顶体缺陷外,还合并精子核超微结构与染色质凝聚异常。提示 FSIP2 变异的表型谱比既往认知更广。

推荐理由

FSIP2 是 NOA/严重畸精的重要遗传学病因;将染色质凝聚异常纳入其表型谱,有助于在基因诊断与遗传咨询中更准确地预判取精与 ICSI 结局。

08-29Reprod ToxicolArticle仅摘要JCR Q2
Assessment of Spermatogenesis Following Bleomycin Treatment in Male Rat Model: The Damage and Recovery Process

在雄性大鼠模型中评估博来霉素(常用抗肿瘤药)对生精的影响:染毒后精子浓度/DNA 碎片率显著异常、生精小管退化,第 60/120 天部分恢复,但血清睾酮等无显著变化。

推荐理由

量化化疗药物对男性生殖的剂量-时间损伤与恢复轨迹,为肿瘤患者治疗前生育力保存决策提供实验依据。

08-28J Vis ExpArticle仅摘要JCR Q3
Clinical Characteristics, Semen Parameters, and Reproductive Hormone Profiles in Infertile Men with Testicular Microlithiasis: A Meta-analysis

系统汇总不育男性中睾丸微石症(TM)的睾丸特征、精液参数与生殖激素谱,并按经典型(CTM)与局限型(LTM)亚组分型。13 项研究合并显示 TM 不育男性中隐睾、睾丸癌、精索静脉曲张合并率分别为 10%、7%、37%。

推荐理由

TM 临床意义长期存争议,该 meta 给出可量化的合并症与精液受损轮廓,为超声发现 TM 后的分层随访与不育评估提供依据。

08-28Urol IntArticle仅摘要JCR Q3
Comparison of Classic Transverse Incision MicroTESE and Modified Mini-Incision MicroTESE in Non-Obstructive Azoospermic Patients

比较经典横切口 mTESE(CTI)与改良小切口 mTESE(MMI)在 NOA 患者中的精子获取率(SRR)、手术时间与术后结局。

推荐理由

mTESE 是 NOA 取精金标准,术式微创化(小切口)能否不牺牲 SRR 并加快康复,直接影响患者选择与医疗成本,是临床实操层面的实用证据。

08-28J Vis ExpArticle仅摘要JCR Q3
Yangjing Capsule Alleviates Spermatogenic Dysfunction in Mice by Inhibiting the QKI-5/p38 MAPK Pathway Through Upregulation of lncRNA NONMMUT031883.2

在环磷酰胺(CP)诱导的小鼠生精障碍模型与 GC-1 精原细胞中,阳精胶囊(YC)剂量依赖性地改善精子质量、性激素与生育力并抑制精原细胞凋亡;机制上通过上调 lncRNA 抑制 QKI-5/p38 MAPK 通路。

推荐理由

为中药改善化疗相关男性生精损伤提供了可机制化的实验证据,对肿瘤幸存者生育力保护具潜在转化价值。

08-28AndrologyArticle仅摘要JCR Q1
Male Sexual and Reproductive Health in Diabetes and Obesity Pharmacotherapy: A Source-Triangulated Counseling Map

梳理降糖/减重药物(如 GLP-1 受体激动剂、SGLT2i 等)如何影响男性性功能与生殖健康,triangulating 临床研究、试验注册、监管标签与专利多源信息形成咨询地图。

推荐理由

糖尿病/肥胖人群中性功能障碍与性腺功能低下高发,药物对睾酮与勃起的影响常被忽视;该地图有助门诊在开药同时给出男性生殖健康咨询。

08-28Sex MedArticleOA全文JCR Q2
Angiotensin (1-7) improves diabetes mellitus-induced erectile dysfunction in rats by modulating the Cav-1/eNOS signaling pathway

在糖尿病诱导的 ED(DMED)大鼠中,血管紧张素 (1-7)(Ang (1-7))通过调控小窝蛋白-1(Cav-1)/内皮型一氧化氮合酶(eNOS)信号改善勃起功能,机制涉及恢复 NO 信号与减轻氧化应激。

推荐理由

为代谢相关 ED 提供不同于 PDE5i 的新干预靶点(RAS 轴),契合 PDE5i 反应欠佳的糖尿病 ED 人群。

08-28Sex MedArticleOA全文JCR Q2
Differential signal strength of male sexual dysfunction associated with antidepressants: a disproportionality analysis of FAERS database

基于 FDA FAERS 不良事件数据库,用不成比例分析系统比较不同抗抑郁药与男性性功能障碍(MSD)的关联强度差异。

推荐理由

抗抑郁药所致 MSD 会反作用于抑郁症状,明确各类药物的相对风险有助于在精神科—男科联合用药中优选对性功能影响更小的方案。

08-28J Mol ModelArticleOA全文JCR Q3
Molecular insights and ADMET profiling of iridoids as candidate leads for erectile dysfunction therapy

对水苦荬(Veronica anagallis-aquatica)中 8 种环烯醚萜苷进行 PDE-5/PDE-6 抑制与选择性计算筛选,发现 catalposide 对 PDE-5 亲和力(-8.6 kcal/mol)优于参考药伐地那非(-8.3)且对 PDE-6 选择性高。

推荐理由

PDE-6 交叉抑制是 PDE5i 视觉副作用的根源,发现高选择性 PDE-5 配体为低副作用 ED 药物研发提供苗头。

08-28Clin BiochemArticle仅摘要JCR Q2
From selective testing to actionable prevention: The VALOR-ED pathway

针对 ED 与疑似性腺功能低下提出 VALOR-ED 五要素检验路径(表型验证、分析适用性、心血管代谢风险、选择性 reflex 检测、可行动报告),连接实验室检验与预防。

推荐理由

直击 ED/性腺低下实验室检测的变异与"检测—预防"脱节问题,为多中心验证与国际基准提供可落地框架。

08-27AndrologyArticle仅摘要JCR Q1
Predictive Models of Pregnancy Based on Male Partner Data From a Preconception Cohort Study

基于孕前队列中男性伴侣的生活方式与行为数据,用机器学习构建自然妊娠预测模型;男性因素约占夫妻不育的 50%,但既往少有以男性综合数据建模者。

推荐理由

把男性生活方式/行为变量纳入受孕预测,可前移不育风险识别窗口,为男科主导的孕前咨询与干预提供数据驱动工具。

08-26Biosens BioelectronArticle仅摘要JCR Q1
Information-driven nanozyme screening enabled sensitive detection of seminal neutral α-glucosidase activity reveals clinical infertility relevance

建立纳米酶增强比色法灵敏检测精液中中性 α-葡萄糖苷酶(NAG,附睾功能标志物),通过信息驱动筛选确定 MnO2 纳米酶,并用 LLM 辅助检索合成路线。

推荐理由

附睾功能标志物的高灵敏检测有望提升男性不育的精液外诊断精度,为无创、低样本量的附睾梗阻/功能评估提供新方法。

2026-08-28 星期五 · 当天 25 条
来源:PubMed(按真实发表日,非收录日)· 每条附 PMID 可核对 · 期刊标注 JCR 分区(Q1–Q4,2024 JCR / 2025-06 发布,SJR 核实)
08-28Eur J PharmacolArticle仅摘要JCR Q1
丙磺舒增强离体大鼠前列腺、膀胱与阴茎海绵体的环核苷酸介导松弛

在离体大鼠前列腺、膀胱与阴茎海绵体证实,丙磺舒(抑制 MRP4/5 外排环核苷酸)可增强 cAMP/cGMP 升高剂的平滑肌松弛,提示老药新用潜力。

推荐理由

LUTS、BPH 与 ED 共享环核苷酸信号且常共存,增强 PDE5i 等药物的局部效应可为难治性 ED 提供联合用药思路。

08-27AndrologyArticle仅摘要JCR Q1
精子 DNA 碎片指数与生活方式因素的关联

探讨精子 DNA 碎片指数(DFI)与临床特征及可改变生活方式因素的关联,并与传统精液参数比较,以明确 DFI 的决定因素与临床意义。

推荐理由

DFI 作为男性不育评估的补充标志物长期受检测异质性困扰,厘清其与生活方式的可修饰关联,有助于在男科门诊把 SDF 纳入更规范的个体化咨询。

08-27AndrologyArticle仅摘要JCR Q1
吴茱萸碱通过抑制 M1 巨噬细胞极化改善高脂相关勃起功能障碍

在高脂血症相关 ED(HLED)大鼠模型中发现,吴茱萸碱(Rutaecarpine)通过抑制巨噬细胞 M1 极化诱导的阴茎海绵体纤维化改善勃起;HLED 对传统 PDE5i 反应差。

推荐理由

针对 PDE5i 疗效欠佳的代谢相关 ED 提供新的抗炎/抗纤维化干预靶点,契合代谢综合征人群 ED 管理难点。

08-26Aging MaleConsensus仅摘要JCR Q2
初级保健中的睾酮缺乏管理:国际专家共识

国际专家就基层医疗场景下睾酮缺乏的筛查、诊断阈值、治疗指征与随访达成共识性建议。

推荐理由

把迟发性性腺功能减退的规范管理前移到初级保健,直接影响大量中年男性的就诊路径。

08-26BJU IntArticle仅摘要JCR Q1
国际登记研究中前列腺癌术后/放疗后的性功能

基于国际登记数据,描述前列腺癌根治术与放疗后患者性功能的真实世界发生与影响因素。

推荐理由

肿瘤幸存者性健康是男科—肿瘤科交界的重要议题,登记数据为共同决策提供基线。

08-24Prostate Cancer Prostatic DisArticle仅摘要JCR Q1
前列腺大小及其对水蒸气热疗后性功能的影响

评估 BPH 水蒸气热疗( convective water vapor thermal therapy, Rezūm)后前列腺体积对性功能(含 ED/射精)的影响。

推荐理由

微创 BPH 治疗对性功能的保留程度是患者决策关键,体积因素提供细化预期。

08-24Graefes Arch Clin Exp OphthalmolArticle仅摘要JCR Q1
勃起功能障碍男性视网膜血管与结构改变的系统综述

系统综述 ED 男性的视网膜微血管/结构改变,呼应"ED 是全身血管内皮功能障碍窗口"的假说。

推荐理由

以眼科无创影像评估内皮功能,为 ED 作为心血管预警标志提供跨科室证据。

08-23AndrologyArticle仅摘要JCR Q1
ARRDC5 在哺乳动物精子发生中的时空表达

刻画 ARRDC5 在精子发生过程中的时空表达模式,提示其在生精调控中的功能。

推荐理由

生精相关新基因的机制阐明,持续丰富男性不育的遗传学图谱。

08-23Orv HetilArticle仅摘要JCR Q4
阴茎假体植入术后的患者满意度与并发症

总结阴茎假体植入术(IPP)后的患者满意度与并发症谱,反映三线 ED 治疗的真实世界结局。

推荐理由

IPP 是重度 ED 的金标准治疗,满意度与并发症数据是医患共同决策的核心依据。

08-22J Assist Reprod GenetArticleOA全文JCR Q2
非梗阻性无精子症中肠道菌群特征与取精结局的关联

刻画 NOA 男性的肠道菌群特征,并评估其与 mTESE 显微取精结局的关联,试图从微生态角度预测手术取精成功率。

推荐理由

把"肠道菌群—生精能力"这条新兴轴推进到临床可转化的取精预测,为有手术指征的 NOA 患者提供非侵入性术前分层线索。

08-21Pharmaceuticals (Basel)Review仅摘要JCR Q1
Incretin 类药物对性腺功能低下男性睾酮水平的影响(PRISMA 系统综述)

按 PRISMA 2020 系统综述 GLP-1/GIP 受体激动剂对男性性腺功能低下睾酮水平的影响,探讨性腺功能低下究竟是 incretin 疗效的风险因素还是该类药物对睾酮有益。

推荐理由

T2DM/肥胖男性中 35–50% 合并性腺功能低下,明确 GLP-1 与睾酮的双向关系,直接影响肥胖相关性腺功能减退的共管策略。

08-21Medicine (Baltimore)ArticleOA全文JCR Q2
原发与复发精索静脉曲张栓塞的技术与静脉造影差异

回顾性分析 92 例精索静脉曲张栓塞(原发 43、显微术后复发 42、既往栓塞复发 7),比较技术成功率与静脉造影特征(反流精索内静脉、侧支等)。

推荐理由

首次系统区分原发与复发精索静脉曲张的栓塞技术差异,为复发型病例的介入路径选择提供实操依据。

08-21Reprod SciReviewOA全文JCR Q2
虾青素与男性生殖健康:机制、实验证据与临床展望(综述)

综述虾青素通过调控氧化还原稳态、保护线粒体完整性、减轻精子脂质过氧化的机制与临床前证据,及其在男性生殖健康中的治疗潜力。

推荐理由

氧化应激是男性不育的核心驱动因素,天然抗氧化剂的循证梳理为临床抗氧化辅助治疗提供可落地的参考框架。

2026-08-27 星期四 · 当天 9 条
来源:PubMed(按真实发表日,非收录日)· 每条附 PMID 可核对 · 期刊标注 JCR 分区(Q1–Q4,2024 JCR / 2025-06 发布,SJR 核实)
08-26Nature Reviews UrologyReview仅摘要JCR Q1(Top综述)
Erectile dysfunction and cardiovascular health

权威综述重申 ED 是心血管疾病的"哨兵"标志,血管性 ED 与冠脉事件存在共同病理生理通路,强调早筛与跨学科管理。

推荐理由

顶刊综述巩固"ED 即心血管预警"的临床共识,对男科—心内科联合门诊的推广有直接支撑。

08-26Trends in Biochemical SciencesReview仅摘要JCR Q1(Top综述)
The structural basis of CatSper function in sperm motility and fertilization

综述原生小鼠 CatSper 通道的最新结构研究,阐明其作为精子超激活运动主 Ca²⁺ 通路的结构基础。

推荐理由

CatSper 是男性不育机制研究与男性避孕靶点最热的结构生物学方向,结构阐明直接指向药物设计。

08-22BiomaterialsArticle仅摘要JCR Q1(Top)
AIE 药理启用的细胞器治疗用于微塑料诱导的弱精症

针对 PTFE 微塑料经线粒体衰竭与铁死亡导致弱精症,提出 AIE 药理启用的细胞器治疗策略。

推荐理由

把"环境微塑料—男性生育力下降"这条新兴公共卫生线索落到可干预靶点,转化意义高。

08-20BiomedicinesReview仅摘要JCR Q2
Recurrent Pregnancy Loss: A Couple-Based Framework for Integrating Paternal Assessment

提出将父方评估整合进复发性流产(RPL)的夫妻同治框架。常规精液分析主要适用于 RPL 合并不育或疑似男性生殖疾病者;精子 DNA 碎片(SDF)是研究最充分的父方生物标志,但结果因检测方法而异。

推荐理由

把"男性因素"从辅助生殖的配角提为 RPL 的系统性评估对象,对男科门诊前置筛查 SDF 有直接临床指引价值。

二、设备与器械 / 临床试验进展
2026-10-12 星期一 · 当天 9 条
来源:ClinicalTrials.gov API v2(overallStatus=RECRUITING,按 LastUpdatePostDate 倒序,仅收近 30 天更新)· 逐条核对日期
2026-09-11 星期五 · 当天 2 条
来源:ClinicalTrials.gov API v2(overallStatus=RECRUITING,按 LastUpdatePostDate 倒序,仅收近 30 天更新)· 逐条核对日期
2026-09-10 星期四 · 当天 1 条
来源:ClinicalTrials.gov API v2(overallStatus=RECRUITING,按 LastUpdatePostDate 倒序,仅收近 30 天更新)· 逐条核对日期
2026-09-09 星期三 · 当天 3 条
来源:ClinicalTrials.gov API v2(overallStatus=RECRUITING,按 LastUpdatePostDate 倒序,仅收近 30 天更新)· 逐条核对日期
2026-09-03 星期四 · 当天 1 条
来源:ClinicalTrials.gov API v2(overallStatus=RECRUITING,按 LastUpdatePostDate 倒序,仅收近 30 天更新)· 逐条核对日期
2026-09-01 星期二 · 当天 3 条
来源:ClinicalTrials.gov API v2(overallStatus=RECRUITING,按 LastUpdatePostDate 倒序,仅收近 30 天更新)· 逐条核对日期
2026-08-29 星期六 · 当天 1 条
来源:ClinicalTrials.gov API v2(overallStatus=RECRUITING,按 LastUpdatePostDate 倒序,仅收近 30 天更新)· 逐条核对日期
08-18ClinicalTrials.govTrial
Adaptions and Resiliency to Multi-Stressor OpeRations(性腺功能低下监测) / NCT06455969

多环境观察性/操作性研究,在多重应激作业场景下监测军人的肌骨损伤、性腺功能低下(hypogonadism)与激素避孕等健康指标,评估适应与韧性。

推荐理由

把性腺功能低下纳入极端生理应激监测体系,拓展了男科(应激性/继发性性腺功能低下)在职业与军事医学中的实时评估场景;其余近 30 天新更新的 RECRUITING 研究多为前列腺癌或女性生育力方向,非男科核心,未纳入。

2026-08-28 星期五 · 当天 12 条
来源:ClinicalTrials.gov API v2(overallStatus=RECRUITING,按 LastUpdatePostDate 倒序,仅收近 30 天更新)· 逐条核对日期
08-26ClinicalTrials.govTrial
射精与性高潮障碍登记研究 / NCT06605469

建立射精与性高潮障碍(含早泄、延迟射精)的真实世界登记队列,系统收集流行病学、评估与诊疗数据。

推荐理由

射精障碍长期缺乏大样本登记数据,该注册研究有望补齐 PE/延迟射精在自然人群中的流行病学与诊疗缺口。

08-20ClinicalTrials.govTrial
活体活动精子分选装置对高龄父方 IVF 结局的影响 / NCT07605182

前瞻性比较 LensHooke® CA0 免离心活体活动精子分选装置与传统密度梯度离心对 ≥40 岁父方 IVF/ICSI 后精子 DNA 碎片、囊胚率与临床妊娠的影响。

推荐理由

针对高龄父方精子 DNA 碎片升高的痛点,免离心分选有望降低氧化损伤、改善辅助生殖结局。

08-19ClinicalTrials.govTrial
蜂王浆补充用于不明原因男性不育 / NCT07337265

评估蜂王浆补充对不明原因男性不育(含精子 DNA 碎片)的干预作用。

推荐理由

针对不明原因不育与 SDF 这一临床难点,天然补充剂的循证化尝试为一线生活方式/营养干预提供新证据。

08-14ClinicalTrials.govTrial
代谢综合征男性 ED 的生活方式干预 / NCT07758842

针对合并代谢综合征的 ED 男性,评估生活方式干预(体重/运动/饮食)对勃起功能的改善。

推荐理由

代谢综合征与 ED 高度共病,生活方式作为可改变的一线干预,对该人群具明确的公共卫生与临床价值。

2026-08-27 星期四 · 当天 4 条
来源:ClinicalTrials.gov API v2(overallStatus=RECRUITING,按 LastUpdatePostDate 倒序,仅收近 30 天更新)· 逐条核对日期
数据源:PubMed · ClinicalTrials.gov 每日 08:00 自动更新 · 本页逐日追加 · 收录全部历史

指南与专家共识 · 年度合集

维护周期:每年更新一次 | 当前版本:2025–2026 年度(持续追踪中)

指南与专家共识更新频率以年计,故独立于每日速览维护。本页按「两类内容」组织:类型一为指南/共识的权威原文(跳转官方/学会/PubMed);类型二为第三方对关键内容的解读文章(便于快速理解)。

如何补充条目? 两条路都行,不必自己填表——
① 把下载好的指南/共识 PDF 或文本发给我,我来解析、提炼要点并补录本表;
② 直接让我去搜索相关解读文章(就像本页类型二已做的那样),我整理后填入。

一、已收录指南 / 共识(权威原文)

国际

名称发布组织年份原文链接一句话要点
EAU 性与生殖健康指南 2026(Sexual and Reproductive Health,limited update of 2025)
类型一
EAU(欧洲泌尿协会)2026 EAU 官网 2026-04-01 发布,纳入 116 项更新研究;重点更新性腺功能减退、射精障碍、阴茎弯曲(Peyronie)、阴茎异常勃起章节,并重组 ED 治疗推荐(5.6.12)逻辑;明确睾酮不用于男性不育/拟生育者、PCa 后睾酮治疗安全边界。
EAU 男性性健康与生殖健康指南:2025 男性不育更新
类型一
EAU(欧洲泌尿协会)2025 PubMed 40118737 男性不育的临床评估(精液分析、激素、影像)、药物治疗(克罗米芬/促性腺激素)、NOA 的 TESE 选择、ED 的多模式管理;2025-03-20 发布。
EAU 男性性健康与生殖健康指南(性腺功能减退、ED、早泄、Peyronie)
类型一
EAU2025 医脉通镜像 ED 个性化治疗决策算法(PDE5i→海绵体注射→假体)、PE 终身性/获得性分型、PD 急性/稳定期区分与手术指征。
Diagnosis and Treatment of Infertility in Men(男性不育诊治)
类型一
AUA / ASRM2024-12 AUA 指南库 男性不育诊断治疗联合指南,强调遗传检测等特定场景;与 2025 EAU 推荐一致。
Diagnosis and Management of Male Chronic Pelvic Pain(男性慢性盆腔痛)
类型一
AUA2024–2025 AUA 指南库 男性慢性盆腔疼痛综合征的诊断与管理的更新版。
第五次国际性医学咨询(ICSM 2024) 性功能障碍定义与分类共识
类型一
ISSM(国际性医学学会)2026 SMR 原文 2024 年国际共识、2026-04 发表于 Sexual Medicine Reviews(14(2):qeag028);为男女共 24 项性功能障碍(男 17 项,含 ED、PE、Peyronie、性欲低下、各类射精/高潮障碍等)建立循证/共识定义并汇总流行病学,统一临床与科研术语。

国内

名称发布组织年份原文链接一句话要点
男性不育及相关生殖健康管理指南
类型一
中国性学会2025 中国男科学杂志 2025;39(6)。覆盖定义/流行病学/评估(精液、内分泌、遗传、影像)/治疗(药物、外科、ART)/生育力保存全流程,强调多学科协作。
勃起功能障碍和早泄共病中西医结合诊治中国专家共识
类型一
中国性学会中医性学分会2024 PDF 原文 ED/PE 共病的中西医结合诊疗定位与辨证(柴胡桂枝汤、温经汤等),基于医生经验+证据+患者意愿的规范化方案。
早泄诊断与治疗指南
类型一
中华医学会男科学分会2022 DOI 原文 2022,28(7):656-665。早泄定义三要素+四分类(原发/继发/自然变异/主观),PEDT 等量表筛查;达泊西汀为国内唯一获批早泄适应证口服药,阶梯化综合治疗。
勃起功能障碍诊断与治疗指南
类型一
中华医学会男科学分会2022 DOI 原文 2022,28(8):722-755。ED 病因-评估-阶梯治疗全流程:基础治疗、PDE5i 一线、ICI 二线、VED/LI-ESWT 辅助、阴茎假体三线;强调心血管共病筛查。
男性不育诊疗指南
类型一
中华医学会男科学分会2022 DOI 原文 2022,28(1):66-76。男性不育定义(未避孕 1 年未孕)、病因分层(精液异常/精索静脉曲张/内分泌/遗传)、阶梯式评估与个体化治疗,强调夫妇同查同治。
精索静脉曲张诊断与治疗指南
类型一
中华医学会男科学分会2022 DOI 原文 2022,28(8):756-767。VC 与男性不育/阴囊痛/睾酮异常相关;诊断分级、保守治疗、显微镜下精索静脉结扎及术后随访的规范化推荐。
早泄诊断与治疗指南(2025版)
类型一
中华医学会男科学分会2025 中华男科学杂志 2025,31(2):121-128。早泄诊疗指南新一版,沿用 ISSM 定义(原发 IELT≈1 min、继发<3 min)并完善四类分型(原发/继发/自然变异/主观),强调病史为诊断核心、达泊西汀一线、中西药联用与伴侣共同参与。

二、解读文章 / 第三方精读(类型二)

以下为各大平台对上面指南关键内容的中文解读,便于快速把握要点(点击跳转原文站点)。

解读标题来源链接对应指南 / 看点
2025 EAU 指南:男性性健康和生殖健康全文解读
类型二
医脉通 医脉通 对应 EAU 2025 SRH 指南;含 ED/PE/PD 治疗推荐表与强度分级。
男性性健康和生殖健康——EAU 指南(2025 更新) 中文解读
类型二
医学界医生站 医学界 对应 EAU 2025 SRH;附证据获取(2021–2024 Medline/EMBASE/Cochrane 系统综述)。
2025 年,男性生殖领域迎来原创性研究的集中爆发
类型二
科学网 科学网 盘点 2025 男性生殖进展,含 EAU 2025 指南要点与 micro-TESE/ICSI 新证据。
勃起功能障碍和早泄共病中西医结合诊治中国专家共识(解读)
类型二
中华医学网 中华医学网 对应 2024 中国 ED/PE 共病共识;病史/检查/中西药联用要点。
2026 EAU 指南:性与生殖健康(中文要点)
类型二
梅斯医学 梅斯医学 对应 EAU 2026 SRH 指南;覆盖性腺功能减退、射精障碍、Peyronie、阴茎异常勃起与 ED 治疗推荐重组的中文要点。
早泄诊断与治疗指南(2022)临床要点解读
类型二
医脉通 医脉通 对应 2022 早泄指南;含药物治疗推荐等级表与中医药辨证论治(肝气郁结/肾气不固/肾阴虚等)。
男性不育诊疗指南(2022)要点解读
类型二
中华医学网 中华医学网 对应 2022 男性不育指南;定义、病因分层、阶梯式诊断流程与个体化治疗要点。
28.7%男性中招!早泄分3类,精准用药对应方案
类型二
网易新闻(科普解读) 网易新闻 对应《早泄诊断与治疗指南(2025版)》;按三分类(原发/继发/主观)讲清用药(达泊西汀一线、SSRI、局麻剂)与手术适应证边界,并转引 ISSM 2025 PE 指南(J Sex Med 2025;22(5):1123-1136)。

三、持续追踪的来源

  • 国际:AUA、ESSM、ISSM、ASRM 指南与共识;EAU 男性不育/性功能障碍章节;Global Andrology Forum(2026 氧化应激相关)。
  • 国内:中华医学会男科学分会 / 泌尿外科学分会、中国性学会相关指南与共识;中华男科学杂志、中国男科学杂志、生殖医学杂志。
  • 专题:ED 诊疗、早泄、Peyronie 病、男性不育评估与精索静脉曲张、性腺功能低下。

四、更新方式

每日速览不重复收录指南;本页由自动化任务在发现指南级更新时(通常每年数次)单独维护,并定期检索新增的「解读文章」补入类型二。你也可随时把指南文件发我,我来补录权威原文(类型一)。